Marianne Stanford

Education

BSc: Memorial University of Newfoundland

MSc: Memorial University of Newfoundland

PhD: Dalhousie University

Postdoctoral Training: Robarts Research Institute/Ottawa Hospital Research Institute

Research interests

Dr. Marianne Stanford is the Asssistant Scientific Director of the Insitute of Infection and Immunity at the Canadian Institute for Health Research (CIHR).  She has expertise in preclinical research activities and clinical immunology assessment of cancer immunotherapies and infectious disease vaccines through her previous work with IMV, Inc. She also serves as adjunct professor in Microbiology and Immunology at Dalhousie University, as a member of the Vaccine Discovery group of the Canadian Centre for Vaccinology, and as an Associate Member of the Beatrice Hunter Cancer Research Institute. Marianne conducted her postdoctoral training at the Robarts Research Institute and at the Ottawa Hospital Research Institute (OHRI), focusing her research on the use of viruses in the development of novel cancer treatments. While at the OHRI, she worked with Jennerex Biotherapeutics (now SillaJen) in the development of Pexa-Vec for human clinical trials. She received her BSc and MSc from Memorial University of Newfoundland and her PhD from Dalhousie University. In her spare time, Marianne is involved in science outreach and policy and is the former Chair of the Canadian Association of Postdoctoral Scholars.

Selected publications

Vila-Leahey A, MacKay A, Portales-Cervantes L, Weir GM, Merkx-Jacques A, Stanford MM. Generation of highly activated, target specific tumor-infiltrating CD8+ T cells induced by a novel T cell targeted immunotherapy. 2020. Oncoimmunology. 27; 9(1): 1782574

Torrey HL, Kaliaperumal V, Bramhecha Y, Weir GM, Falsey AR, Walsh EE, Langley JM, Schepens B, Saelens X, and Stanford MM. Evaluation of the protective potential of antibody and T cell responses elicited by a novel preventative vaccine towards Respiratory Syncytial Virus Small Hydrophobic Protein. 2020. Human Vaccines and Immunotherapeutics. 16 (9): 2007-2017.

Evgin, L., Vaha-Koskela M., Rintoul, J., LeBoeuf F., Falls, T., Barrett J.W., Bell, J.C. and Stanford, M.M. Potent oncolytic activity of raccoonpox virus in the absence of natural pathogenicity. 2010. Molecular Therapy. 18(5):896-902.

Stanford, M.M., Barrett, J.W, Nazarian S.H, Werden, S., and McFadden G. Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells. 2007 Journal of Virology. 81(3): 1251-60