Helping improve cardiac care and health through discovery
With cardiovascular disease as the leading cause of death in Canada, Dalhousie Medicine New Brunswick (DMNB) research scientists are working to improve the lives of many. Our three researchers are focused on:
- stem cell regeneration
- lipids and their linkages to diabetes and heart disease
- fat and the body’s ability to metabolise it
Cellular cleansing rejuvenates heart
Dr. Thomas Pulinilkunnil aims to identify and characterize novel molecular and physiological mechanisms that influence heart’s ability to degrade, dispose and recycle cellular waste. Therapeutic targeting of these biochemical pathways during diabetes, obesity, aging, and coronary heart disease will improve heart function and decrease mortality.
Why fat matters to the heart
Dr. Petra Kienesberger is working to advance our understanding of heart disease in obesity and diabetes. Her laboratory is examining how obesity and diabetes trigger excess fat deposition in and around the heart and how this affects heart function.
Cellular adaptation to cardiovascular therapy/treatment
Dr. Keith Brunt’s laboratory is focused on translational medicine, with a major interest in understanding how cells adapt to stress in order to develop innovative therapeutic strategies to treat cardiovascular disease.