Deniz Top
Assistant Professor
Email: dtop@dal.ca
Mailing Address:
5850 College Street, Room 10-J1
Sir Charles Tupper Medical Building
PO Box 15000
Halifax, Nova Scotia, Canada B3H 4R2
Sir Charles Tupper Medical Building
PO Box 15000
Halifax, Nova Scotia, Canada B3H 4R2
Education
- PhD, Dalhousie University
Academic Positions
- Department member since 2022
Research Topics:
- Circadian rhythms, sleep, feeding, learning/memory behaviours, transcriptional regulation, protein biochemistry
Research
Dr. Top’s laboratory uses an innovative interdisciplinary approach, combining biochemistry, neurobiology and behavioural studies to understand how behaviour is regulated at molecular resolution in the model organism Drosophila melanogaster. In addition to understanding the fundamental mechanisms that govern behaviour, the Top lab also seeks to understand the molecular etiology of mental illness, which is estimated to affect 1 in 3 Canadians in their life time.
Current Lab Members
| Myra Ahmed | Research Assistant (Pharmacology) |
|---|---|
| Olya Akay | Research Assistant (Pharmacology) |
| Joshua Avery | Grad Student (MSc) |
| Peter Johnstone | Lab Manager |
| Mia Schofield | Grad Student (MSc, Pharmacology) |
Publications
- Ahmad M, Li W, Top D. Integration of Circadian Clock Information in the Drosophila Circadian Neuronal Network. J Biol Rhythms. 2021 Jun;36(3):203-220. [PubMed] [Article]
- Kummeling J, Stremmelaar DE, Raun N, et al. Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome. Mol Psychiatry. 2021 Jun;26(6):2013-2024. [PubMed] [Article]