Deniz Top

Assistant Professor

top

Email: dtop@dal.ca
Mailing Address: 
5850 College Street, Room 10-J1
Sir Charles Tupper Medical Building
PO Box 15000
Halifax, Nova Scotia, Canada B3H 4R2
 

Education

  • PhD, Dalhousie University

Academic Positions

  • Department member since 2022

Research Topics:

  • Circadian rhythms, sleep, feeding, learning/memory behaviours, transcriptional regulation, protein biochemistry

Research

Dr. Top’s laboratory uses an innovative interdisciplinary approach, combining biochemistry, neurobiology and behavioural studies to understand how behaviour is regulated at molecular resolution in the model organism Drosophila melanogaster. In addition to understanding the fundamental mechanisms that govern behaviour, the Top lab also seeks to understand the molecular etiology of mental illness, which is estimated to affect 1 in 3 Canadians in their life time.

Current Lab Members

Myra Ahmed Research Assistant (Pharmacology)
Olya Akay Research Assistant (Pharmacology)
Peter Johnstone Lab Manager
Mia Schofield Grad Student (MSc, Pharmacology)

Publications

  1. Ahmad M, Li W, Top D. Integration of Circadian Clock Information in the Drosophila Circadian Neuronal Network. J Biol Rhythms. 2021 Jun;36(3):203-220. [PubMed] [Article]
  2. Kummeling J, Stremmelaar DE, Raun N, et al. Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome. Mol Psychiatry. 2021 Jun;26(6):2013-2024. [PubMed] [Article]