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Rafael Garduno

Professor - Adjunct

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Department of Microbiology & Immunology

Email: rafael.garduno@inspection.gc.ca
Phone: 902-536-1008
Mailing Address: 
Canadian Food Inspection Agency Dartmouth Laboratory 1992 Agency Drive Dartmouth Nova Scotia Canada B2B 1Y9
 
Research Topics:
  • Bacteriology
  • Cell Biology
  • Microbial Pathogenesis
  • Legionella Pneumophila
  • Listeria Monocytogenes
  • Chaperonin
  • Host Pathogen Surface Interactions
  • Developmental Biology

 

Education

BSc, National School of Biological Sciences, Mexico City, Mexico
PhD, University of Victoria, BC, Canada
Postdoctoral Training, University of Victoria, BC, University of South Dakota, SD Dalhousie University, NS

Research interests

Interests in food- and water-borne pathogens and their relationships between fitness and virulence.  Focus on Legionella pneumophila, (waterborne, cause of Legionnaires’ Disease) particularly on (i) the mature infectious form (MIF) believed to be its natural transmissive form; (ii) surface-associated Legionella chaperonin and its effects on eukaryotic cells.

Selected publications

  • Nasrallah, G.K., E. Gagnon, D.J. Orton, and R.A. Garduño.  2011.  The htpAB operon of Legionella pneumophila cannot be deleted in the presence of the groE chaperonin operon of Escherichia coli.  Can. J. Microbiol. 57: 943-952.
  • Nasrallah, G.K., A.L. Riveroll, A. Chong, L.E. Murray, P.J. Lewis, and R.A. Garduño.  2011.  Legionella pneumophila requires polyamines for optimal intracellular growth.  J. Bacteriol. 193: 4346-4360.  Author correction for this paper: J. Bacteriol. 194: 3032, 2012 (Issue Number 11).
  • Garduño, R.A., A. Chong, G.K. Nasrallah, and D.S. Allan.  2011.  The Legionella pneumophila chaperonin – an unusual multifunctional protein in unusual locations.  Front. Microbiol. 2:122. doi:10.3389/fmicb.2011.00122
  • Chong, A., C.A. Lima, D.S. Allan, G.K. Nasrallah, and R.A. Garduño. 2009.  The purified and recombinant Legionella pneumophila chaperonin alters mitochondrial trafficking and microfilament organization.  Infect. Immun. 77: 4724-4739.
  • View additional publications on PubMed

Selected awards and honours

  • Tier II Canada Research Chair in food- and water-borne bacterial pathogens.  CRC Program – Natural Sciences and Engineering Research Council.
  • Award of Excellence in Medical Research - Basic Science.  Dalhousie Medical Research Foundation and the Faculty of Medicine, Dalhousie University.
  • IMPSS Faculty Appreciation Award.  Immunology, Microbiology and Pathology Students Society, Dalhousie University.
  • Izaak Walton Killam Postdoctoral Fellowship.  Dalhousie University.

Other interests and achievements

  • Bacterial degradation of paralytic shellfish toxins. Inventors: Thomas A. Gill, Carrie Donovan and Rafael A. Garduño.  Application number 60/976,557.  Filed in the United States of America Patent and Trademark Office on October 1, 2007.  Provisional patent granted on November 2009.
  • Member of the Editorial Board of the Canadian Journal of Microbiology, Infection and Immunity Section, since 2004.
  • Co-chair of Local Organizing Committee, and Scientific Program coordinator – 55th Annual Conference of the Canadian Society of Microbiologists, Halifax, NS, June 2005.