Angelo Iulianella
Professor

Related information
Email: angelo.iulianella@dal.ca
Phone: 902-494-7738
Mailing Address:
Department of Medical Neuroscience,
Dalhousie University,
Life Sciences Research Institute, Room N343, 1348 Summer Street, Halifax, Nova Scotia
, Canada
B3H 4R2
Research Topics:- Neural development
- Neurogenesis
- Maintenance of neural phenotypes
- Cell fate
- Peripheral nervous system
- Neural crest cells
- Embryology
Education
- Bsc (McGill)
- PhD (Montreal)
- PFD (Stowers Institute for Medical Research)
Research interests
Dr. Iulianella is a developmental biologist interested in the molecular and cellular events that lead to formation of distinct cell types in the nervous system. He is also studying the formation of newborn neurons in both the developing and postnatal brain. Through these investigations he hopes to uncover genetic pathways that can be used to reactivate neurogenic (neuron-forming) programs in brains suffering from neurodegenerative diseases and oxidative stress.
Selected publications
- Kurosaka, H., Trainor. P.A., Leroux-Berger, M., and Iulianella, A. (2015). Cranial nerve formation requires Shh signaling cross-talk with the canonical Wnt pathway to maintain neural crest-placode cell interactions. PLoS One. 10(3):e0120821.
- Yamada, M., Clark, J., McClelland, C., Capaldo, E., Ray, A., and Iulianella, A. (2015). Cux2 defines a sub-population of neurogenic progenitors in the hippocampus. Hippocampus. 25: 253-268. Cover article.
- Yamada, M., Clark, J., and Iulianella, A (2014). MLLT11/AF1q is differentially expressed in maturing neurons during development. Gene Expression Patterns. 15: 80-87.*Corresponding author.
- Wittmann, W., Iulianella, A.*, and Gunhaga, L. (2014). Cux2 acts as a critical regulator for neurogenesis in the olfactory epithelium of vertebrates. Developmental Biology. 388: 35-47.
- Kurosaka, H., Iulianella, A., Williams, T., and Trainor, P.A. (2014). Disrupting hedgehog and WNT signaling promotes cleft lip pathogenesis. Journal of Clinical Investigation.124: 1660-1671. Cover article.
- Iulianella, A., Sharma, M., Vanden Heuvel, G.B., and Trainor, P.A. (2009). Cux2 (Cutl2) Functions downstream of Notch Signaling to regulate dorsal interneuron formation in the spinal cord. Development. 136: 2329-34.
- Iulianella, A., Sharma, M., Durnin, M., Vanden Heuvel, G.B., and Trainor, P.A. (2008). Cux2 (Cutl2) integrates neural progenitor development with the cell cycle progression during spinal cord neurogenesis. Development. 135: 729-741.
Memberships
- Society for Developmental Biology
- Canadian Association for Neuroscience