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Publications

Al-Banna N, Pavlovic D, Bac VH, Utpatel K, Janke E, Rippke JN, Borowiak M, Cerny V, Spassov A, Johnston B, Issekutz TB, Lehmann C. Acute administration of antibiotics modulates intestinal capillary perfusion and leukocyte adherence during experimental sepsis. Int J Antimicrob Ag (submitted) - Supplementary Material [PDF - 125 KB]

Lehmann C, Götz F, Schuster L, Zhou J. Improved setup for intestinal intravital microscopy in mice - the "floating table". Minerva Anestesiol. 2012 Jul 6.

Spassov A, Gredes T, Pavlovic D, Gedrange T, Lehmann Ch, Leszczyszyn J, Gerber H, Dominiak M, Skóra J, Lucke S, Kunert-Keil Ch: Talin, vinculin and nestin expression in orofacial muscles of dystrophin deficient mdx mice. Arch Immunol Ther Exp (Warsz). 2012 Apr;60(2):137-43.

Zhou J, Pavlovic D, Willecke J, Friedel C, Whynot S, Hung O, Vladimir C, Lehmann, C. Activated protein C reduces endotoxemia induced leukocyte adherence and improves capillary perfusion within the pial microcirculation in experimental endotoxemia. Microvasc Res. 2012 May;83(3):276-80.

Küster, I., R. Kuschnereit, M.E.M. Kelly, J. Zhou, S. Whynot, M. Kianian, O. Hung, R. Shukla, V. Cerny, D. Pavlovic, Ch. Lehmann. Cannabinoid 1 receptor antagonist causes seizures during anesthesia in experimental sepsis. Anesth Analg. 2012 Jun;114(6):1217-9.

Lehmann C, Kianian M, Zhou J, Küster I, Kuschnereit R, Whynot S, Hung O, Shukla R, Johnston B, Cerny V, Pavlovic P, Spassov A and Kelly MEM. Cannabinoid receptor 2 activation reduces intestinal leukocyte recruitment and systemic inflammatory mediator release in acute experimental sepsis. Critical Care 2012 Mar 15;16(2):R47.

Truhlar, A., Z. Turek, R. Skulec, Ch. Lehmann, D. Pavlovic, V. Cerny: Terlipressin/adrenaline is better than adrenaline alone in a porcine model of prolonged ventricular fibrillation A randomized controlled study. Signa Vitae. 2012; 7(1): 10 – 16.

Lehmann C, Sharawy N, Pavlovic D: Metabolomics of steroid effects during sepsis. Med Hypotheses, 2012 Jun 1.

Lehmann C, D Pavlovic, J Zhou, U Wuttke, D Saeger, A Spassov, O Hung, V Cerny, T Witter, S Whynot, U Suchner, B Alteheld, P Stehle, M Gründling: Intravenous free and dipeptide-bound glutamine maintains intestinal microcirculation in experimental endotoxemia. Nutrition 2012 Jan 3.

Lehmann C, Kianian M, Zhou J, Cerny V, Kelly M. The endocannabinoid system in sepsis - a potential target to improve microcirculation? Signa Vitae. 2011;6(1):7-13.

Zhou, J., M. Schmidt, B. Johnston, F. Wilfart, S. Whynot, O. Hung, M. Murphy, V. Cerny, D. Pavlovic, Ch. Lehmann: Experimental endotoxemia induces leukocyte adherence and plasma extravasation within the rat pial microcirculation. Phys Res. 2011 Oct 12.

Sharawy N, Pavlovic D, Wendt M, Cerny V, Lehmann C: Evaluation of the effects of gender and estradiol treatment on the intestinal microcirculation during experimental sepsis. Microvasc. Res. 2011; 82: 397-403.

Spassov A, Gredes T, Gedrange T, Lucke S, Pavlovic D, Lehmann C, Kunert-Keil C: The expression of Myogenic Differentiation Factor 1 and Myogenin in regenerated masticatory muscles of Dystrophic (mdx) Mice is not elevated. J Orofac Orthoped. 2011; 72: 469-475.

Turek Z, Parizkova R, Samek J, Lehmann C, Kaska M, Cerny V: Differential effects of intravenous anesthetics on hepatosplanchnic microcirculation in rats: Sidestream dark-field imaging study. Clin Hemorheol Microcirc. 2011 Dec 16.

Hübner N-O, Daeschlein G, Lehmann C, Musatkin S, Kohlheim U, Gibb A, Assadian O, Kobayashi H. Microbiological safety and cost-effectiveness of weekly breathing circuit changes in combination with heat moisture exchange filters: a prospective longitudinal clinical survey. GMS Krankenhaushygiene interdisziplinär. 2011 Jan;6(1):Doc15.

Sitina, M., Turek, Z., Parizkova, R., Lehmann, C., & Cerny, V. Preserved cerebral microcirculation in early stages of endotoxemia in mechanically-ventilated rabbits. Clinical Hemorheology and Microcirculation, 2011: 46, 1-8.

Pavlovic, D., Spassov, A., & Lehmann, C. Euthanasia: In Defense of A Good, Ancient Word. Journal of Clinical Research Bioethics, 2011; 02(01), 1-5.

Wetzel B., R. Kuse, D. Pavlovic, A. Gibb, H. Merk, Ch. Lehmann, M. Wendt, T.I. Usichenko: The effect of auricular acupuncture on fentanyl requirement during hip arthroplasty – a randomized controlled trial. Clin J Pain 2011 Mar-Apr;27(3):262-7.

Zhou J., V. Cerny and Ch. Lehmann: Fructose – the sweet poison. J Parent Ent Nutr 2011, Mar;35(2):158-9.

Kranabetter R, Kramer A, Rathgeber J, Züchner K, Assadian O, Daeschlein G, · Hübner NO, Dietlein E, Exner M, Gründling M, Lehmann Ch, Wendt M, Graf BM, Holst D, Jatzwauk L, Puhlmann B, Welte T, Wilkes AR: Infektionsprävention bei der Narkosebeatmung durch Einsatz von Atemsystemfiltern. Anaesthesist. 2010 · 59:1124–1132.

Fuchs Ch., E. Ladwig, J. Zhou, D. Pavlovic, K. Behrend, S. Whynot, O. Hung, M. Murphy, V. Cerny and Ch. Lehmann: Argatroban administration reduces leukocyte adhesion and improves capillary perfusion within the intestinal microcirculation in experimental sepsis. Thromb Hemost 2010 Aug 30;104(5).

Landsberger, M., J. Zhou, S. Wilk, C. Thaumüller, D. Pavlovic, M. Otto, S. Whynot, O. Hung, M. Murphy, V. Cerny, St. Felix, Ch. Lehmann: Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats. Critical Care 2010:14,R223.

Sitina M, Turek Z, Parizkova R, Cerny V. In situ assessment of the brain microcirculation in mechanically-ventilated rabbits using Sidestream dark-field (SDF) imaging. Physiol Res. 2010, Oct. 15.

Skulec R, Truhlář A, Seblová J, Dostál P, Cerný V. Pre-hospital cooling of patients following cardiac arrest is effective using even low volumes of cold saline. Crit Care. 2010 Dec 22;14(6):R231.

 Kramer A, Kranabetter R, Rathgeber J, Zuchner K, Assadian O, Daeschlein G, Hubner N O, Dietlein E, Exner M, Grundling M, Lehmann C, Wendt M, Graf B M, Holst D, Jatzwuak L, Puhlmann B, Welte T, Wilkes A R. Infection prevention during anaesthesia ventilation by the use of breathing system filters (BSF): Joint recommendation by Gernam Society of Hospital Hygiene (DGKH) and German Society for Anaesthesiology and Intensive Care (DGAI). GMS Krankenhhyg Interdiszip. 2010 Sep 21; 5(2).

 Matejovic M, Chvojka J, Sykora R, Krouzecky A, Radej J, Parizkova R, Dostal P, Novak I, Cerny V. 24-Hour Intensivist Shift: The Biological Pathways between Job Stress and Health. JIMR. 2010; 627.

 Fuchs C, Ladwig E, Zhou J, Pavlovic D, Behrend K, Whynot S, Hung O, Murphy M, Cerny V, Lehmann C. Argatroban administration reduces leukocyte adhesion and improves capillary perfusion within the intestinal microcirculation in experimental sepsis. Thromb Haemost. 2010 Aug 30;104(5).

Richter J, Zhou J, Pavlovic D, Scheibe R, Bac VH, Blumenthal J, Hung O, Murphy MF, Whynot S, Lehmann C. Vancomycin and to lesser extent tobramycin have vasomodulatory effects in experimental endotoxemia in the rat. Clin Hemorheol Microcirc. 2010 Jan 1;46(1):37-49.

Skulec R, Truhlár A, Dostál P, Seblová J, Knor J, Dostálová G, Skulec S, Cerny V. Prehospital cooling by cold infusion: searching for the optimal infusion regimen. Emerg Med J. 2010 Aug 23.

Boettger, S. F., Pavlovic, D., Gründling, M., Wendt, M., Hung, O., Henzler, D., Kern, H. R., and Lehmann, C. (2010) Comparison of arterial pressure cardiac output monitoring with transpulmonary thermodilution in septic patients. Medical science monitor : international medical journal of experimental and clinical research, 16(3), PR1-7.

Grundling M, Rickert S, Saeger D, et al. Acute high-dose sodium selenite administration improves intestinal microcirculation without affecting cytokine release in experimental endotoxemia. Journal of Trace Elements in Medicine and Biology. 2009;23:138-143.

Gründling M, Kuhn S, Lehmann C, Wendt M. Prophylaxe der Sepsis - Infektionsprävention, Hygienerichtlinien undAkutmanagement. Der Klinikarzt. 2009;38(4):188-192.

Lehmann C, Holtfreter B. About small particles and small numbers in sepsis research. Crit Care Med. 2009;37(6):2131-2132.

Milchert M, Spassov A, Meissner K, et al. Skeletal muscle relaxants inhibit rat tracheal smooth muscle tone in vitro.Journal of Physiology and Pharmacology. 2009;60(Suppl. 8):5-11.

Pavlovic D, Lehmann C, Wendt M. For an indeterministic ethics. The emptiness of the rule in dubio pro vita and life cessation decisions. Philos Ethics Humanit Med. 2009;4:6.

Scheibe R, Schade M, Gründling M, et al. Glutamine and alanyl-glutamine dipeptide reduce mesenteric plasma extravasation, leukocyte adhesion, and tumor necrosis factor-alpha release during experimental endotoxemia.Journal of Physiology and Pharmacology. 2009;60(Suppl. 8):19-24.

Birnbaum J, Klotz E, Spies CD, et al. The combinations C1 esterase inhibitor with coagulation factor XIII and N-acetylcysteine with tirilazad mesylate reduce the leukocyte adherence in an experimental endotoxemia in rats. ClinHemorheol Microcirc. 2008;40(3):167-176.

Birnbaum J, Lehmann C, Klotz E, et al. Effects of N-acetylcysteine and tirilazad mesylate on intestinal functional capillary density, leukocyte adherence, mesenteric plasma extravasation and cytokine levels in experimentalendotoxemia in rats. Clin Hemorheol Microcirc. 2008;39(1-4):99-111.

Grundling M, Lehmann C, Saeger D, et al. Response of the rat intestinal microcirculation to experimentalendotoxemia is attenuated by ampicillin but not by its derivative KKP723. Clin Hemorheol Microcirc. 2008;38(3):163-170.

Lehmann C, Murphy M, Chisholm J, Hung O. Nitric oxide inhalation and glucocorticoids--can there be a belt-and-braces approach in sepsis? Crit Care Med. 2008;36(11):3109-3110.

Lehmann C, Scheibe R, Schade M, et al. Effects of activated protein C on the mesenteric microcirculation and cytokine release during experimental endotoxemia. Can J Anaesth. 2008;55(3):155-162.

Lietz P, Schmidt R, Hosemann W, et al. Acupuncture of specific points influences cortical auditory evoked potentials--a volunteer crossover study. Acupunct Electrother Res. 2008;33(1-2):1-8.

Meissner K, Iber T, Roesner JP, et al. Successful transtracheal lung ventilation using a manual respiration valve: an in vitro and in vivo study. Anesthesiology. 2008;109(2):251-259.

Pavlovic D, Frieling H, Usichenko T, et al. s-Carboxymethylcysteine inhibits carbachol-induced constriction of epithelium-denuded rat and human airway preparations. Clin Exp Pharmacol Physiol. 2008;35(5-6):663-669.

Usichenko TI, Edinger H, Witstruck T, et al. Millimetre wave therapy for pain relief after total knee arthroplasty: a randomised controlled trial. Eur J Pain. 2008;12(5):617-623.

Usichenko TI, Lehmann C, Ernst E. Auricular acupuncture for postoperative pain control: a systematic review of randomised clinical trials. Anaesthesia. 2008;63(12):1343-1348.

Wesolowski T, Lotze M, Domin M, et al. Acupuncture reveals no specific effect on primary auditory cortex: a functional magnetic resonance imaging study. Neuroreport. 2008.

Angstwurm MW, Engelmann L, Zimmermann T, et al. Selenium in Intensive Care (SIC): results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock. Crit Care Med. 2007;35(1):118-126.

Birnbaum J, Spies CD, Klotz E, et al. Iloprost for additional anticoagulation in continuous renal replacement therapy--a pilot study. Ren Fail. 2007;29(3):271-277.

Frieling H, Lauer KS, Grundling M, et al. Peritoneal instillation of taurolidine or polihexanide modulates intestinal microcirculation in experimental endotoxemia. Int J Colorectal Dis. 2007;22(7):807-817.

Lehmann C, Feyerherd F, Feyerherd T, et al. Ketamine does not affect intestinal microcirculation in pentobarbital-anaesthetized rats during experimental endotoxaemia. Lab Anim. 2007;41(1):55-62.

Lustig MK, Bac VH, Pavlovic D, et al. Colon ascendens stent peritonitis--a model of sepsis adopted to the rat: physiological, microcirculatory and laboratory changes. Shock. 2007;28(1):59-64.

Usichenko TI, Kuchling S, Witstruck T, et al. Auricular acupuncture for pain relief after ambulatory knee surgery: a randomized trial. Cmaj. 2007;176(2):179-183.

Birnbaum J, Hein OV, Luhrs C, et al. Effects of coagulation factor XIII on intestinal functional capillary density, leukocyte adherence and mesenteric plasma extravasation in experimental endotoxemia. Crit Care. 2006;10(1):R29.

Birnbaum J, Klotz E, Spies CD, et al. Effects of dopexamine on the intestinal microvascular blood flow and leukocyte activation in a sepsis model in rats. Crit Care. 2006;10(4):R117.

Frieling H, Grundling M, Lauer KS, et al. Intraperitoneal instillation of polihexanide produces hypotension and vasodilation: in vivo and in vitro study in rats. Int J Colorectal Dis. 2006;21(4):373-380.

Lehmann C, Meissner K, Knock A, et al. Activated protein C improves intestinal microcirculation in experimentalendotoxaemia in the rat. Crit Care. 2006;10(6):R157.

Lehmann C, Bac VH, Pavlovic D, et al. Metronidazole improves intestinal microcirculation in septic rats independently of bacterial burden. Clin Hemorheol Microcirc. 2006;34(3):427-438.

Pavlovic D, Frieling H, Lauer KS, et al. Thermostatic tissue platform for intravital microscopy: 'the hanging drop' model. J Microsc. 2006;224(Pt 2):203-210.

Usichenko TI, Dinse M, Hermsen M, et al. Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study. Pain. 2005;114(3):320-327.

Hannich HJ, Hartmann U, Lehmann C, et al. Biofeedback as a supportive method in weaning long-term ventilated critically ill patients. Med Hypotheses. 2004;63(1):21-25.

Lehmann C, Birnbaum J, Luhrs C, et al. Effects of C1 esterase inhibitor administration on intestinal functional capillary density, leukocyte adherence and mesenteric plasma extravasation during experimental endotoxemia.Intensive Care Med. 2004;30(2):309-314.

Birnbaum J, Lehmann C, Stauss HM, et al. Sympathetic modulation of intestinal microvascular blood flow oscillations in experimental endotoxemia. Clin Hemorheol Microcirc. 2003;28(4):209-220.

Lehmann C, Georgiew A, Weber M, Birnbaum J, Kox WJ. Reduction in intestinal leukocyte adherence in rat experimental endotoxemia by treatment with the 21-aminosteroid U-74389G. Intensive Care Med. 2001;27(1):258-263.

Lehmann C, Konig JP, Dettmann J, Birnbaum J, Kox WJ. Effects of iloprost, a stable prostacyclin analog, on intestinal leukocyte adherence and microvascular blood flow in rat experimental endotoxemia. Crit Care Med. 2001;29(7):1412-1416.

Lehmann C, Taymoorian K, Wauer H, et al. Effects of the stable prostacyclin analogue iloprost on the plasma disappearance rate of indocyanine green in human septic shock. Intensive Care Med. 2000;26(10):1557-1560.

Pulletz S, Lehmann C, Volk T, et al. Influence of heparin and hirudin on endothelial binding of antithrombin in experimental thrombinemia. Crit Care Med. 2000;28(8):2881-2886.

Lehmann C, Egerer K, Georgiew A, et al. Inhibition of tumor necrosis factor-alpha release in rat experimentalendotoxemia by treatment with the 21-aminosteroid U-74389G. Crit Care Med. 1999;27(6):1164-1167.

Luther B, Lehmann C, Grune T, et al. [Controlled reperfusion of ischemic extremity musculature to prevent free radical induced lesions]. Zentralbl Chir. 1999;124(4):336-343.