Seminar
Dr. Vanessa DeLey Cox
Senior Scientist, Molecular Sciences Group, Illumina (San Diego, USA)
Protein engineering enables novel chemistry for DNA sequencing
Time
Starts:
Ends:
Location
Virtual
Additional Information
Summary: Why and how XLEAP chemistry was developed at Illumina. Global shipping at ambient temperature required entirely revolutionizing Illumina’s patented sequencing chemistry. Nucleotides in particular rapidly degrade at ambient temperature. However, while a novel set of stable nucleotides resolved one problem, it required entirely new SBS (sequencing-by-synthesis) chemistry, including a new, engineered polymerase.