Manuel Mattheisen, MD
- Community Health and Epidemiology
- Genetic Epidemiology
- Molecular Genetics (especially in complex traits)
- Genome-wide Association Studies (GWAS)
- Polygenic Risk Scoring (PRS)
- Genomics and Epigenomics
Dr. Mattheisen received his MD from the University of Bonn and holds joint appointments in the Faculty of Medicine's Department of Community Health and Epidemiology and the Faculty of Computer Science. He furthermore is Adjunct Professor at the LMU in Germany, and the Karolinska Institute in Sweden. As a physician with a strong background in genetic epidemiology, biostatistics, bioinformatics, and molecular genetics, Dr. Mattheisen's research focuses on translating genetic findings into clinical diagnostics and care in a global mental health setting (with close collaborators in East and South Asia, Africa, North and South America, and Europe). His lab is dedicated to four main areas of research: identifying genetic risk factors for complex traits through large-scale studies; characterizing genetic predictors of disease onset, course, and treatment response; evaluating patient-oriented factors that impact clinical implementation; and developing and enhancing biostatistical and bioinformatic methods and tools. The underlying motivation for this work is to connect knowledge bases across phenomics, molecular genetics and biostatistics/bioinformatics as a foundation in all four research domains.