Phone: (902) 494-1086
Lab: (902) 494-3883
- Host-pathogen interaction
- Influenza A virus
- Cellular stress responses
- RNA granules
BSc: National Taras Shevchenko University, Kyiv, Ukraine
PhD: State University of New York at Buffalo, Buffalo, NY
Postdoctoral Training: Dalhousie University, Halifax, NS
We study virus-host interactions with a focus on intrinsic cell defense mechanisms and their subversion by influenza viruses. Another area of interest in the lab is the biology of stress granules – cytoplasmic foci of messenger RNA-protein complexes that form in response to various types of stress, including viral infections
For a full list of Dr. Khaperskyy's publications, click here.
McCormick, C. and Khaperskyy, D.A. (2017) Translation inhibition and stress granules in the antiviral immune response. Nat. Rev. Immunol. 10:647-660.
Khaperskyy, D.A., Schmaling, S., Larkins-Ford, J., McCormick, C., and Gaglia, M.M. (2016) Selective degradation of host RNA polymerase II transcripts by influenza A virus PA-X host shutoff protein. PLoS Pathog. 12: e1005427.
Khaperskyy, D.A., Emara, M. M., Johnston, B.P., Anderson, P., Hatchette, T.F., and McCormick, C. (2014) Influenza A virus host shutoff disables antiviral stress-induced translation arrest. PLoS Pathog. 10: e1004217.
Khaperskyy, D.A., Hatchette, T.F., and McCormick, C. (2012) Influenza A virus inhibits cytoplasmic stress granule formation. FASEB J. 26: 1629-39.
- MICI 4114 Advanced virology
- MICI 3620 Experiential learning
I am not recruiting graduate students at the moment.