Sir Charles Tupper Medical Building, Room 7C
5850 College Street
PO Box 15000
Halifax Nova Scotia Canada B3H 4R2
- Cancer Biology
- NKT Cells
- Leukocyte Homing
BSc, University of Calgary
PhD, University of Calgary
Postdoctoral Training, Stanford University
Research focuses on immune cell development, homing, and activation. We are currently studying the regulation of autoimmunity and anti-tumour immune responses by natural killer T (NKT) cells, a subset of leukocytes that bridge the innate and adaptive immune systems.
- Vienotte L, Gebremeskel S, Johnston B. 2016. CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFN-γ production and tumor control. Oncoimmunology 5:e1160979
- Gebremeskel S, Slauenwhite D, Johnston B. 2016. Reconstitution models to evaluate natural killer T cell function in tumor control. Immunol. Cell Biol. 94:90-100
- Slauenwhite D, Johnston B. 2015. Mechanisms regulating NKT cell localization in homeostasis and infection. Front. Immunol. 6:255.
- Gebremeskel S, Clattenburg DR, Slauenwhite D, Lobert L, Johnston B. 2015. Natural killer T cell activation overcomes immunosuppression to enhance clearance of postsurgical breast cancer metastasis in mice. Oncoimmunology 4:e995562.
- Slauenwhite D, Gebremeskel S, Doucette CD, Hoskin DW, Johnston B. 2014. Regulation of cytokine polarization and T cell recruitment to inflamed paws in mouse collagen-induced arthritis by the chemokine receptor CXCR6. Arthritis & Rheum. 66:3001-3012.
Selected awards and honours
- Canada Research Chair in Inflammation and Immunity (2004-2014)
- David T. Janigan Teaching Award (2011)