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Brent Johnston

Professor

B Johnston portrait 1

Email: brent.johnston@dal.ca
Phone: 902-494-5131
Fax: 902-494-5125
Mailing Address: 
Department of Microbiology and Immunology
Dalhousie University
Sir Charles Tupper Medical Building, Room 7C
5850 College Street
PO Box 15000
Halifax Nova Scotia Canada B3H 4R2
 
Research Topics:
  • Cancer Biology
  • Immunology
  • Inflammation
  • Cytokines
  • Chemokines
  • NKT Cells
  • Leukocyte Homing

 

Education

BSc, University of Calgary
PhD, University of Calgary
Postdoctoral Training, Stanford University

Research interests

Research focuses on immune cell development, homing, and activation.  We are currently studying the regulation of autoimmunity and anti-tumour immune responses by natural killer T (NKT) cells, a subset of leukocytes that bridge the innate and adaptive immune systems.

Featured publications
 

For a complete list of Dr. Brent Johnston's publications, click here.

  • Vienotte L, Gebremeskel S, Johnston B. 2016. CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFN-γ production and tumor control. Oncoimmunology 5:e1160979

  • Gebremeskel S, Slauenwhite D, Johnston B. 2016. Reconstitution models to evaluate natural killer T cell function in tumor control. Immunol. Cell Biol. 94:90-100

  • Slauenwhite D, Johnston B. 2015. Mechanisms regulating NKT cell localization in homeostasis and infection. Front. Immunol. 6:255.

  • Gebremeskel S, Clattenburg DR, Slauenwhite D, Lobert L, Johnston B. 2015. Natural killer T cell activation overcomes immunosuppression to enhance clearance of postsurgical breast cancer metastasis in mice. Oncoimmunology 4:e995562.

  • Slauenwhite D, Gebremeskel S, Doucette CD, Hoskin DW, Johnston B. 2014. Regulation of cytokine polarization and T cell recruitment to inflamed paws in mouse collagen-induced arthritis by the chemokine receptor CXCR6. Arthritis & Rheum. 66:3001-3012.

Selected awards and honours

  • Canada Research Chair in Inflammation and Immunity (2004-2014)
  • David T. Janigan Teaching Award  (2011)