Sir Charles Tupper Medical Building, Room 7-C
5850 College Street
PO Box 15000
Halifax Nova Scotia Canada B3H 4R2
- Microbial Pathogenesis
- Molecular Mechanisms of Virulence
- Protein Secretion Systems and Toxin Biology
- Microbiome and Gastrointestinal Disease
- Molecular and Cellular Biology
- Enteric Bacterial Pathogens
BSc (Honours), Queens University
PhD, Queen’s University
Postdoctoral Training, University of British Columbia, Michael Smith Laboratory
My laboratory emphasizes a cross-disciplinary approach to studying host-pathogen interactions, using techniques in the areas of molecular microbiology, genetics, cell biology, immunology, cell structure, signaling, and protein biochemistry.
- Ramu T, Prasad ME, Connors E, Mishra A, Thomassin JL, Leblanc J, Rainey J, Thomas NA. 2013. A novel C-terminal region within the multicargo type III secretion chaperone CesT contributes to effector secretion. Journal of Bacteriology.
- Thomas NA, Ma I, Prasad M and Rafuse C. 2012. Expanded Roles for Multicargo and Class 1B Effector Chaperones in Type III Secretion. Journal of Bacteriology.
- Thomas NA, Deng W, Puente JL, Frey EA, Yip C, Strynadka N, Finlay BB. 2005. CesT is a multi-effector chaperone and recruitment factor required for the efficient type III secretion of both LEE and non-LEE encoded effectors of enteropathogenic Escherichia coli. Molecular Microbiology 57: 1762-1779. Highlighted by Faculty of 1000
- Yip CK, Kimbrough TG, Felise HB, Vuckovic M, Thomas NA, Pfuetzner RA, Frey EA, Finlay BB, Miller SI, Strynadka NCJ. 2005. Structural characterization of the molecular platform for type III secretion system assembly. Nature 435: 702-707. An influential structural biology paper characterizing the type III secretion system of pathogens.
- View additional publications on PubMed
Selected awards and honours
- CIHR New Investigator (2007-2012)
- MSHRF Postdoctoral Award
- NSERC Postdoctoral Award
- CIS Academic All Canadian - Soccer