Tim Lee



Email: tim.lee@dal.ca
Mailing Address: 
Department of Microbiology and Immunology
Dalhousie University
Sir Charles Tupper Medical Building 5850 College Street
PO Box 15000
Halifax Nova Scotia Canada B3H 4R2
Research Topics:
  • Cell Biology
  • Immunology
  • Inflammation
  • Transplant Rejection
  • CD8+ T Cell Development and Function
  • B Cells
  • Memory T Cells



BSc, University of Toronto (Microbiology)
MSc, University of Toronto (Microbiology)
PhD, Glasgow University (Immunology)
Postdoctoral Training, McMaster University (Pathology), University of Calgary (Immunology)

Research interests

Dr. Lee's major research interest is in late graft rejection of cardiac transplants. The focus of the research in his laboratory is the etiology of the occlusive intimal lesion in coronary arteries after transplantation and the role of CD8+ T cells and B cells in the development of chronic rejection.

Selected publications

  • Devitt, J.J., Hirsch, G.M., Rice, A. and Lee T.D.G. 2013.  Impact of donor benign intimal thickening on cardiac allograft vasculopathy. Journal of  Heart and Lung Transplantation 32:454-460 (PMID: 23498165)
  • Gareau, A.J., Nashan, B, Hirsch, G.M. and Lee T.D.G. 2012. Cyclosporine immunosuppression does not prevent the production of donor specific antibody capable of mediating allograft vasculopathy.  Journal of Heart and Lung Transplantation 31:874-880. (PMID 22554675)
  • Hart-Matyas, M., Nejat, S., Jordan, J., Hirsch, G., and Lee, T.D.G. 2010. IFN-g and Fas/FasL pathways cooperate to induce medial cell loss and neointimal lesion formation in allograft vasculopathy.  Transplantation Immunology 22:157-164. (PMID 19895889)
  • Nejat, S., Zaki, A., Hirsch, G., and Lee, T.D.G. 2008 CD8+ T cells mediate aortic allograft vasculopathy under conditions of calcineurin immunosuppression: Role of IFN-γ and CTL mediators. Transplant Immunology 19:103-111. (PMID 18503885)

Selected awards and honours

  • 2010    Professor of the Year Award, Dalhousie Medical School
  • 2009   Academic All Canadian Mentor, Dalhousie University
  • 1998    Association of Atlantic Universities Distinguished Teacher Award
  • 1998    Dalhousie Alumni Award for Teaching Excellence

Other interests and achievements

  • runner - 2004 winner (age bracket) Bluenose 10K
  • yoga
  • jazz clarinet  (no prizes for my clarinet playing!)