Joanne Langley, MD
Division Head Infectious Diseases, Professor
IWK Health Centre
Goldbloom RCC Pavilion, 4th Floor
5850/5980 University Ave.
Halifax, NS B3K 6R8
- Vaccines, vaccine preventable infectious diseases
- Child health, infections in children
- Evidence-based immunization policy
- Respiratory infections, communicable disease control
- Professor, Departments of Pediatrics and Community Health & Epidemiology, Faculty of Medicine; Member, Faculty of Graduate Studies, Dalhousie University
- Canadian Institutes of Health Research – GlaxoSmithKline Chair in Pediatric Vaccinology, Dalhousie University
- Active Staff, Pediatric Infectious Diseases, IWK Health Centre; Infection Prevention and Control Services
BA, Queen’s University at Kingston
MD, Dalhousie University
MSc (Clinical Epidemiology), McMaster University
Fellow, Royal College of Physicians and Surgeons of Canada (Pediatrics, Infectious Diseases), University of Toronto
Dr. Langley is a pediatric infectious disease physician in the Department of Pediatrics and is cross-appointed in the Department of Community Health and Epidemiology in the Faculty of Medicine. She is based at the IWK Health Centre and the Canadian Center for Vaccinology. She conducts studies on the prevention of infectious diseases using vaccines, from phase 1 (first in humans) through to efficacy trials (phase 3) and post-marketing studies of how well vaccines work when they are used in immunization programs (phase 4). These studies are done with collaborators in public health, industry, universities, and non-governmental organizations. Dr. Langley has a particular interest in prevention of respiratory infections such as Respiratory Syncytial Virus and influenza. Her work also focuses on vaccine policy and evidence-based decision making in immunization programs. She is a former member of the Canadian Task Force on Preventive Health Care and Canada’s National Advisory Committee on Immunization (Chair, 2007-2011), and serves as an advisor on several immunization decision making expert groups. She is an active investigator in the Canadian Immunization Research Network and leads its Clinical Trials Network (CTN).
- Langley JM, Aggarwal N, Toma A, Halperin SA, McNeil SA, Fissette L, Dewé W, Leyssen M, Toussaint JF, Dieussaert I. A Randomized, Controlled, Observer-Blinded Phase 1 Study of the Safety and Immunogenicity of a Respiratory Syncytial Virus Vaccine With or Without Alum Adjuvant. J Infect Dis. 2017 Jan 1;215(1):24-33. doi: 10.1093/infdis/jiw453. Epub 2016 Sep 29. PubMed PMID: 27694633; PubMed Central PMCID: PMC5225248.
- Langley JM. Vaccine Prevention of Respiratory Syncytial Virus Infection in Older Adults: The Work Continues. J Infect Dis. 2017 Dec 12;216(11):1334-1336. doi: 10.1093/infdis/jix504. PubMed PMID: 29029125.
- Langley JM, MacDougall DM, Halperin BA, Swain A, Halperin SA, Top KA, McNeil SA, MacKinnon-Cameron D, Marty K, De Serres G, Dubé E, Bettinger JA. Rapid surveillance for health events following a mass meningococcal B vaccine program in a university setting: A Canadian Immunization Research Network study. Vaccine. 2016 Jul 25;34(34):4046-9. doi: 10.1016/j.vaccine.2016.06.025. Epub 2016 Jun 11. PubMed PMID: 27302338.
- ElSherif MS, Brown C, MacKinnon-Cameron D, Li L, Racine T, Alimonti J, Rudge TL, Sabourin C, Silvera P, Hooper JW, Kwilas SA, Kilgore N, Badorrek C, Ramsey WJ, Heppner DG, Kemp T, Monath TP, Nowak T, McNeil SA, Langley JM, Halperin SA; Canadian Immunization Research Network. Assessing the safety and immunogenicity of recombinant vesicular stomatitis virus Ebola vaccine in healthy adults: a randomized clinical trial. CMAJ. 2017 Jun 19;189(24):E819-E827. doi: 10.1503/cmaj.170074. PubMed PMID: 28630358; PubMed Central PMCID: PMC5478408.
- Langley JM, MacDonald LD, Weir GM, MacKinnon-Cameron D, Ye L, McNeil S, Schepens B, Saelens X, Stanford MM, Halperin SA. A respiratory syncytial virus vaccine based on the small hydrophobic protein ectodomain presented with a novel lipid-based formulation is highly immunogenic and safe in adults: a first-in-humans study. J Infect Dis. 2018; 218(3):378–387. PubMed PMID: 29617814.
- Halperin SA, Langley JM, Ye L, MacKinnon-Cameron D, Elsherif M, Allen VM, Smith B, Halperin BA, McNeil SA, Vanderdooi OG, Dwinnell S, Wilson RD, Tapiero B, Boucher M, Le Saux N, Gruslin A, Vaudry W, Chandra S, Dobson S, Money D. A randomized controlled trial of the safety and immunogenicity of tetanus, diphtheria, and acellular pertussis vaccine immunization dring pregnancy and subsequent infant immune response. Clin Infect Dis. 2018;67(7):1063–1071. PubMed PMID: 30010773.
- View additional publications on PubMed