Joanne Langley, MD

Affiliations

• Professor, Departments of Pediatrics and Community Health & Epidemiology, Faculty of Medicine; Member, Faculty of Graduate Studies, Dalhousie University
• Canadian Institutes of Health Research – GlaxoSmithKline Chair in Pediatric Vaccinology, Dalhousie University
• Active Staff, Pediatric Infectious Diseases, IWK Health Centre

Education

BA, Queen’s University at Kingston
MD, Dalhousie University
MSc (Clinical Epidemiology), McMaster University
Fellow, Royal College of Physicians and Surgeons of Canada (Pediatrics, Infectious Diseases), University of Toronto

Research interests

Dr. Langley is a pediatric infectious disease physician in the Department of Pediatrics and is cross-appointed in the Department of Community Health and Epidemiology in the Faculty of Medicine. She is based at the IWK Health Centre and the Canadian Center for Vaccinology. She conducts studies on the prevention of infectious diseases using vaccines, from phase 1 (first in humans) through to efficacy trials (phase 3) and post-marketing studies of how well vaccines work when they are used in immunization programs (phase 4). These studies are done with collaborators in public health, industry, universities, and non-governmental organizations. Dr. Langley has a particular interest in prevention of respiratory infections such as Respiratory Syncytial Virus and influenza. Her work also focuses on vaccine policy and evidence-based decision making in immunization programs. She is a member of the COVID-19 Science Expert Panel, and of the Expert Group on Health Systems of the Chief Science Advisor of Canada, and a former member of the Canadian Task Force on Preventive Health Care and Canada’s National Advisory Committee on Immunization (Chair, 2007-2011), and serves as an advisor on several immunization decision making expert groups. She is an active investigator in the Canadian Immunization Research Network and leads its Clinical Trials Network (CTN).

Selected publications

• Shoukat A, Wells CR, Langley JM, Singer BH, Galvani AP. Projecting demand for critical care beds during COVID-19 outbreaks in Canada. CMAJ. 2020 Apr 8. pii: cmaj.200457. PubMed PMID: 32269020
• Hopman HA, Crowcroft NS, Cesuroglu T, Langley JM. Incorporation of health economic evaluation into immunization policy-making in Canada: Barriers and facilitators. Vaccine. 2020;38(11):2512–2518. PubMed PMID: 32057578.
• Langley JM, Gantt S, Quach C, Bettinger JA, Halperin SA, Mutch J, MacNeil SA, Ward BJ, MacKinnon-Cameron D, Lingun Y, Marty K, Scheifele, Brown E, Alcantara J, and the Canadian Immunization Research Network. Randomized trial of 2 schedules of meningococcal B vaccine in adolescents and young adults, Canada. Emerg Infect Dis. 2020;26(3):454–462. PubMed PMID: 32091358      
  
• Langley JM, MacDonald LD, Weir GM, MacKinnon-Cameron D, Ye L, McNeil S, Schepens B, Saelens X, Stanford MM, Halperin SA. A respiratory syncytial virus vaccine based on the small hydrophobic protein ectodomain presented with a novel lipid-based formulation is highly immunogenic and safe in adults: a first-in-humans study. J Infect Dis. 2018; 218(3):378–387. PubMed PMID: 29617814.
  
• Halperin SA, Langley JM, Ye L, MacKinnon-Cameron D, Elsherif M, Allen VM, Smith B, Halperin BA, McNeil SA, Vanderdooi OG, Dwinnell S, Wilson RD, Tapiero B, Boucher M, Le Saux N, Gruslin A, Vaudry W, Chandra S, Dobson S, Money D. A randomized controlled trial of the safety and immunogenicity of tetanus, diphtheria, and acellular pertussis vaccine immunization during pregnancy and subsequent infant immune response. Clin Infect Dis. 2018;67(7):1063–1071. PubMed PMID: 30010773.
• ElSherif MS, Brown C, MacKinnon-Cameron D, Li L, Racine T, Alimonti J, Rudge TL, Sabourin C, Silvera P, Hooper JW, Kwilas SA, Kilgore N, Badorrek C, Ramsey WJ, Heppner DG, Kemp T, Monath TP, Nowak T, McNeil SA, Langley JM, Halperin SA; Canadian Immunization Research Network. Assessing the safety and immunogenicity of recombinant vesicular stomatitis virus Ebola vaccine in healthy adults: a randomized clinical trial. CMAJ. 2017 Jun 19;189(24):E819-E827. doi: 10.1503/cmaj.170074. PubMed PMID: 28630358; PubMed Central PMCID: PMC5478408.
• View additional publications on PubMed