Services & Equipment
Our Services
Services available in English and French. / Services disponibles en français et en anglais.
We provide a wide range of mass spectrometry (MS) services across several omics fields, including proteomics, metabolomics and lipidomics. We offer sample processing, peptides desalting, MS data acquisition and even data analysis services! Examples of available MS-services include:
- Bottom-up proteomics (Data-Dependent and -Independent Acquisition, DDA and DIA respectively)
- Lipidomics (Untargeted and Targeted)
- Targeted compound and drug monitoring
- HPLC-UV purification and detection
- Variety of validated sample preparation routines
- Computational hardware and bioinformatic services
- Customized analyses (contact bms@dal.ca for more information)
How much does it cost to use our services?
Every project is different! We have carefully curated cost-models that are always changing based on the fluctuating costs of reagents and the designs of different types of experiments. Please reach out to us at bms@dal.ca for accurate costing of your project if you are just curious or you need the information for a grant proposal.
Our Equipment
Orbitrap Fusion Lumos mass spectrometer
The Orbitrap Fusion Lumos is built on the Tribrid architecture and includes quadrupole mass filter, linear ion trap and Orbitrap mass analyzers. System specifications: resolving power up to 500,000 FWHM, with isotopic fidelity up to 240,000 FWHM at m/z 200; Synchronous Precursor Selection (SPS) for MS and MSn experiments; scan rates of up to 30 Hz in OTMSn, and up to 40 Hz in ITMSn; <3 ppm RMS using external calibration. The Lumos can be interfaced to the ACQUITY M-Class UPLC system for nano-micro flow rate experiments, as well as the Vanquish UPLC for analytical flow rate work. The Lumos can optionally be used with the FAIMS Pro ion mobility interface for greater sensitivity in a variety of analysis types.
QExactive mass spectrometer
The QExactive is a quadrupole-Orbitrap platform capable of analyzing a variety of complex sample types. System specifications: Resolving power up to 140,000; Maximum scan speed of 12 Hz at a resolution setting of 17,500 @ m/z 200; Intra-scan dynamic range of 5000:1; <3ppm RMS mass accuracy; 50 to 6,000 m/z mass range. The QExactive is interfaced to a Vanquish UPLC system for sample introduction at analytical flow rates.
QTRAP 5500 mass spectrometer
The QTRAP 5500 mass spectrometer from AB Sciex offers a robust and reliable platform for targeted and other types of directed mass spectrometry experiments. The instrument offers fast and sensitive scanning to facilitate robust and reliable monitoring of target analytes. The QTRAP 5500 is interfaced with an Agilent 1290 Infinity II UPLC system (with a Multisampler module capable of holding thousands of samples) and can be operated with the SELEXion ion mobility interface to enhance overall specificity of data acquisition.
Other equipment
The BMS CORE houses a variety of other instruments and hardware devices that support sample processing and analysis. This includes: thermomixers; SpeedVac centrifuge; HPLC hardware for fractionation/purification/desalting; SPE manifold and vacuum manifold; data processing workstations; and all the reagents you require for sample processing and analysis!
