Christopher D. Richardson
Professor and Canada Research Chair, Tier1
Email: chris.richardson@dal.ca
Phone: 902-494-6876
Mailing Address:
Dalhousie University
Sir Charles Tupper Medical Building, Room 7-C
5850 College Street
PO Box 15000
Halifax Nova Scotia Canada B3H 4R2
- Virology
- Cancer Biology
- Vaccinology
- Oncolytic Viruses
- Tumour Cell Markers
- Liver Cancer
- Measles
- Hepatitis C
Education
BSc, University of British Columbia
MSc, University of British Columbia
PhD, University of British Columbia
Postdoctoral Training, Rockefeller University; National Institutes of Health USA
Research interests
My research involves the molecular biology of measles, canine distemper, hepatitis C, and hepatitis B viruses. We are particularly interested in virus-host cell receptor interactions. Many of these receptors have been found to be highly up-regulated on cancer cells and can be targeted for therapy by recombinant oncolytic viruses.
Selected publications
- Noyce R.S. and Richardson C.D. (2012) Nectin 4 is the Epithelial Cell Receptor for Measles Virus. Trends Microbiol. 20(9):429-39
- Noyce R., Bondre D., Ha M., Sisson G., Tsao M., and Richardson C.D. (2011). The tumor cell marker PVRL4/Nectin 4 is an epithelial cell receptor for measles virus. PLoS Pathogens7(8): e1002240
- Hsu, E.C., His, B., Hirota-Tsuchihara, M., Ruland, J., Iorio, C., Sarangi, F., Diao, J., Migliaccio, G., Tyrrell, D.L., Kneteman, N., and Richardson, C.D. (2003). Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers. Nature Biotechnology 21: 519-525
- Dörig, R., Marcil, A., Chopra, A., and Richardson, C.D. (1993). The human CD46 molecule is a receptor for measles virus (Edmonston strain). Cell 75, 295-305.
- View additional publications on PubMed
Selected awards and honours
- Violet and Blythe Eagles Graduate Prize in Biochemistry 1976
- Bernard Fields Lecturer ; Symposium speaker at the American Society of
- Virology (Montreal, July 10-14, 2004)
- Canada Research Chair Tier I, Dalhousie University (September 2006-2020)
- IWK Health Centre “Research Star of the Year” March 2012
Other interests and achievements
- CIHR Virology and Viral Pathogenesis Grant Panels (1992-2007; 2012)
- NIH Virology B Grant Panel (2011, 2012, 2013)
- National CIHR Training Program in Hepatitis C