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Christopher D. Richardson

Professor and Canada Research Chair, Tier1

chris richardson-2

 

Related information

 

Department of Microbiology & Immunology

Email: chris.richardson@dal.ca
Phone: 902-494-6876
Mailing Address: 
Department of Microbiology and Immunology
Dalhousie University
Sir Charles Tupper Medical Building, Room 7-C
5850 College Street
PO Box 15000
Halifax Nova Scotia Canada B3H 4R2
 
Research Topics:
  • Virology
  • Cancer Biology
  • Vaccinology
  • Oncolytic Viruses
  • Tumour Cell Markers
  • Liver Cancer
  • Measles
  • Hepatitis C

Education

BSc, University of British Columbia
MSc, University of British Columbia
PhD, University of British Columbia
Postdoctoral Training, Rockefeller University; National Institutes of Health USA

Research interests

My research involves the molecular biology of measles, canine distemper, hepatitis C, and hepatitis B viruses. We are particularly interested in virus-host cell receptor interactions. Many of these receptors have been found to be highly up-regulated on cancer cells and can be targeted for therapy by recombinant oncolytic viruses.

Selected publications

  • Noyce R.S. and Richardson C.D. (2012) Nectin 4 is the Epithelial Cell Receptor for Measles Virus. Trends Microbiol. 20(9):429-39
  • Noyce R., Bondre D., Ha M., Sisson G., Tsao M., and Richardson C.D.  (2011).  The tumor cell marker PVRL4/Nectin 4 is an epithelial cell receptor for measles virus.  PLoS Pathogens7(8): e1002240
  • Hsu, E.C., His, B., Hirota-Tsuchihara, M., Ruland, J., Iorio, C., Sarangi, F., Diao, J., Migliaccio, G., Tyrrell, D.L., Kneteman, N., and Richardson, C.D. (2003).  Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers.  Nature Biotechnology 21: 519-525
  • Dörig, R., Marcil, A., Chopra, A., and Richardson, C.D. (1993).  The human CD46 molecule is a receptor for measles virus (Edmonston strain).  Cell 75, 295-305.
  • View additional publications on PubMed

Selected awards and honours

  • Violet and Blythe Eagles Graduate Prize in Biochemistry 1976
  • Bernard Fields Lecturer ; Symposium speaker at the American Society of
  • Virology (Montreal, July 10-14, 2004)
  • Canada Research Chair Tier I, Dalhousie University (September 2006-2020)
  • IWK Health Centre “Research Star of the Year” March 2012

Other interests and achievements

  • CIHR Virology and Viral Pathogenesis Grant Panels (1992-2007; 2012)
  • NIH Virology B Grant Panel (2011, 2012, 2013)
  • National CIHR  Training Program in Hepatitis C