David W. Hoskin
Sir Charles Tupper Medical Building, Room 7D1
5850 College Street
PO Box 15000
Halifax Nova Scotia Canada B3H 4R2
- Cancer Biology
- Antimicrobial Peptides
- Iron Metabolism
- Natural Products
BSc, McGill University
PhD, McGill University
Postdoctoral Training, Samuel Lunenfeld Research Institute, University of Toronto
Professor Hoskin’s research interests include the anti-cancer and anti-inflammatory potential of iron chelating agents, antimicrobial peptides, and phytochemicals found in common spices, fruits, and vegetables; and the manipulation of T cell signal transduction using natural source compounds and other novel agents for cancer control. His work is geared towards developing new treatments for breast cancer and other common cancers.
For a full listing of Dr. David Hoskin's publications, click here.
- A.L. Greenshields, T.G. Shepherd, and D.W. Hoskin. 2017. Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate. Mol. Carcinog. 56:75-93.
- M.R. Power Coombs, M.E. Harrison, and D.W. Hoskin. 2016. Apigenin inhibits the inducible expression of programmed death ligand 1 by human and mouse mammary carcinoma cells. Cancer Lett. 380:424-433.
- W. Fernando, M. Power Coombs, D.W. Hoskin, and H.P.V. Rupasinghe. 2016. Docosahexaenoic acid acylated-phloridzin, a novel polyphenol fatty acid ester derivative, is cytotoxic to breast cancer cells. Carcinogenesis 37:1004-1013.
- A.L. Greenshields, C.D. Doucette, K.M. Sutton, L. Madera, H. Annan, P.B. Yaffe, A. Knickle, Z. Dong, and D.W. Hoskin. 2015. Piperine inhibits the growth and motility of triple-negative breast cancer cells. Cancer Lett. 357:129-140.
- C.D. Doucette, A.L. Greenshields, R. Liwski, and D.W. Hoskin. 2015. Piperine blocks interleukin-2-driven cell cycle progression in CTLL-2 T lymphocytes by inhibiting multiple signal transduction pathways. Toxicol. Lett. 234:1-12.
Selected awards and honours
- Beatrice Hunter Cancer Research Institute Honorary Membership
- David T. Jannigan Teaching Award (Department of Pathology, 2010)
- Distinguished Service Award, Faculty of Graduate Studies, Dalhousie University
- Canadian Breast Cancer Foundation - Atlantic Region Endowed Chair in Breast Cancer Research
- Educator of the Year Award (Department of Microbiology & Immunology, 2002)
- MICI 3115: Immunology
Memberships/Services and Activities
- Senior Scientist -Beatrice Hunter Cancer Research Institute (Honorary Membership)
- Member – American Association for Cancer Research
- Member – Editorial Board of Cancer Letters
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