Anthony OtleyMD, MSc

Division Head Pediatric Gastroenterology, Professor, Associate Chair of Research (Pediatrics)

Phone: 902-470-8746
Fax: 902-470-7249
Mailing Address: 
IWK Health Centre
PO Box 9700
5850-5980 University Ave.
Halifax, NS B3K 6R8
Research Topics:
  • Clinical research
  • Clinical trials
  • Pediatric outcome measures
  • Patient-reported measures (quality of life; symptoms)
  • Inflammatory bowel disease
  • Enteral nutrition for treatment of Crohn’s disease


  • BSc [1987] (University of Western Ontario)
  • MSc (Epidemiology) [2004] (University of Toronto)
  • MD [1991] (University of Toronto)
  • FRCPC [1996] (Dalhousie University)
  • Pediatric Gastroenterology [1999] (University of Toronto)

Clinical interests

Pediatric gastroenterology, hepatology and nutrition, with special interest in pediatric inflammatory bowel disease.

Research interests

Major research interests include clinical trials, and in particular the development and evaluation of outcome measures used in pediatric clinical trials. Other research areas include use of enteral nutrition as primary therapy in the management of Crohn’s disease, with special interest in understanding the role the gut flora may have to play. He is the Maritime principal investigator of the CHILD-CIHR Canadian pediatric IBD Network, and is leading the patient engagement work for this project. He is the pediatric lead, and Maritime key applicant for the IMAGINE SPOR Network studying the microbiome in patients with IBD and IBS.

Selected publications (from last 24 months)

  • KA Dunn, J Moore-Connors, B MacIntyre, A Stadnyk, NA Thomas, A Noble, G Mahdi, M Rashid, AR Otley, JP Bielawski, J Van Limbergen. The gut microbiome of pediatric Crohn’s disease patients differs from healthy controls in genes that can influence the balance between a healthy and dysregulated immune response. Inflamm Bowel Dis. 2016 Nov;22(11):2607-2618
  • Turpin WEspin-Garcia OXu WSilverberg MSKevans DSmith MIGuttman DSGriffiths APanaccione ROtley AXu LShestopaloff KMoreno-Hagelsieb GGEM Project Research ConsortiumPaterson ADCroitoru K. Association of host genome with intestinal microbial composition in a large healthy cohort. Nat Genet. 2016 Nov;48(11):1413-1417. doi: 10.1038/ng.3693. Epub 2016 Oct 3
  • Marcovitch LNissan AMack DOtley AHussey SMclean BLewis MCroft NBarakat FM, Griffiths AM, Turner D. Item Generation and Reduction Towards Developing a Patient Reported Outcome for Pediatric Ulcerative Colitis (TUMMY-UC). J Pediatr Gastroenterol Nutr. 2016 May 6. [Epub ahead of print]
  • Bray J, Fernandes A, Nguyen GC, Otley AR, Heatherington J, Stretton J, Bollegala N, Benchimol EI. The Challenges of Living with Inflammatory Bowel Disease: Summary of a Summit on Patient and Healthcare Provider Perspectives. Can J Gastroenterol Hepatol. Canadian Journal of Gastroenterology and Hepatology, Feb 2016 Volume 2016, Article ID 9430942, 5 pages
  • M Inman, A Otley, T Dummer, Y Cui, MH Schmidt, L Parker. Childhood Exposure to Ionizing Radiation from Computed Tomography Imaging in Nova Scotia, Canada. Paediatr Child Health. 2015 Oct;20(7):381-5
  • JD Lewis, EZ Chen, RN Baldassano, AR Otley, AM Griffiths, D Lee, K Bittinger, A Bailey, ES Friedman, C Hoffmann, L Albenberg, R Sinha, C Compher, E Gilroy, L Nessel, A Grant, C Chehoud, H Li, GD Wu, FD Bushman. Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn’s Disease.  Cell Host Microbe. 2015 Oct 14;18(4):489-500
  • J Van Limbergen, J Haskett, AM Griffiths, J Critch, H Huynh, N Ahmed, JC deBruyn, R Issenman, W El-Matary, TD Walters, C Kluthe, M Roy, E Sheppard, WV Crandall, S Cohen, FM Ruemmele, A Levine, AR Otley. Towards Enteral Nutrition in the treatment of pediatric Crohn’s disease in Canada: a workshop to identify barriers and enablers. Can J Gastroenterol Hepatol. 2015 Oct;29(7):351-6

Selected awards and honours

  • 2015, Outstanding Physician of the Year – Inaugural recipient, presented by Crohn’s and Colitis Canada, at their Annual Meeting October 24th, 2015, Toronto, ON
  • 2011, Award for Excellence in Patient and Family-Centered Care, presented by the IWK Health
  • 2011, Centre Family Leadership Council, presented at the IWK Annual General Meeting
  • 2004-2009, Clinical Research Scholar Award, Faculty of Medicine, Dalhousie University, Halifax, NS.

Professional Memberships (Current)

  • Member, American Association of the Study of Liver Disease
  • Member, American College of Gastroenterology
  • Member, American Gastroenterology Association
  • Member, Canadian Association of Gastroenterology
  • Member, Canadian Medical Association
  • Member, Canadian Pediatric Society
  • Member, North American Society of Pediatric Gastroenterology, Hepatology and Nutrition
  • Fellow, Royal College of Physicians and Surgeons of Canada
  • Professional Member, Crohn’s and Colitis Canada
  • Professional Member, Crohn’s and Colitis Foundation of America

International Medical Activities

  • MicroResearch Mentor/Tutor, Nairobi, Kenya (November, 2016)
  • MicroResearch Mentor/Tutor, Kampala, Uganda (September, 2015)
  • MicroResearch Mentor/Tutor, Nairobi, Kenya (October, 2012)
  • Selian Lutheran Hospital, Arusha, Tanzania (July-August, 2007)  Providing adult and pediatric clinical care, and teaching to medical interns/house officers