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David Hoskin

Professor and Canadian Breast Cancer Foundation - Atlantic Region Endowed Chair in Breast Cancer Research

Department of Pathology

Email: d.w.hoskin@dal.ca
Phone: 902-494-6509
Fax: 902-494-5125
Mailing Address: 
Department of Microbiology and Immunology
Dalhousie University
Sir Charles Tupper Medical Building, Room 7D1
5850 College Street
PO Box 15000
Halifax Nova Scotia Canada B3H 4R2
 
Research Topics:
  • Cancer Biology
  • Immunology
  • Inflammation
  • Antimicrobial Peptides
  • Iron Metabolism
  • Natural Products

Education

  • BSc, McGill University
  • PhD, McGill University
  • Postdoctoral Training, Samuel Lunenfeld Research Institute, University of Toronto

Research interests

Professor Hoskin’s research interests include the anti-cancer and anti-inflammatory potential of natural source compounds, including antimicrobial peptides and phytochemicals found in common spices, fruits, and vegetables; and the manipulation of T lymphocyte signal transduction using natural source compounds and other novel agents for cancer control. His work is geared towards developing new treatments for breast cancer and other common cancers.

Selected publications

  • C.D. Doucette, A. Hilchie, R. Liwski, and D.W. Hoskin. 2013. Piperine, a dietary phytochemical, inhibits angiogenesis. J. Nutr. Biochem. 24:231-239.
  • K. Sutton, C.D. Doucette, and D.W. Hoskin. 2012. NADPH quinine oxidoreductase 1 mediates breast cancer cell resistance to thymoquinone-induced apoptosis. Biochem. Biophys. Res. Comm. 426:421-426.
  • A. Hilchie, C.D. Doucette, D. Pinto, A. Patrzykat, S. Douglas, and D.W. Hoskin. 2011. Pleurocidin-family cationic antimicrobial peptides are cytolytic for breast carcinoma cells and prevent growth of tumor xenografts. Breast Cancer Res. 13: R102 (Editor’s Pick).
  • J.L. Watson, R. Hill, P.B. Yaffe, A. Greenshields, M. Walsh, P.W. Lee, C.A. Giacomantonio, andD.W. Hoskin. 2010. Curcumin causes superoxide anion production and p53-independent apoptosis in human colon cancer cells. Cancer Lett. 297: 1-8.

Selected awards and honours

  • Beatrice Hunter Cancer Research Institute Honorary Membership
  • David T. Jannigan Teaching Award (Department of Pathology, 2010)
  • Distinguished Service Award, Faculty of Graduate Studies, Dalhousie University
  • Canadian Breast Cancer Foundation - Atlantic Region Endowed Chair in Breast Cancer Research
  • Educator of the Year Award (Department of Microbiology & Immunology, 2002)

Other interests and achievements

  • Cancer Letters Editorial Board Member
  • Canadian Breast Cancer Foundation - Atlantic Region Board of Directors Member