Department of Pathology

Dalhousie University

Dr Lisandra Cubero Herrera

Assistant Professor

lisandracuberoherrera
Department of Pathology

Email: lherrera@dal.ca
Phone: 902 473 2808
Research Topics:
  • Forensic & Clinical Toxicology
  • Liquid Chromatography
  • Tandem Mass Spectometry
  • Method Development & Validation
  • Drugs of Abuse Testing
  • Theraputic Drug Monitoring

Biography 

Dr. Lisandra Cubero Herrera is the Scientific Officer in the Toxicology Laboratory at the Department of Pathology and Laboratory Medicine, and an Assistant Professor of Pathology at Dalhousie University. Her research interests include the development of methods for drugs of abuse and therapeutic drug monitoring.

Dr. Cubero has developed and validated mass spectrometry-based methods for screening and confirmation of opioids such as fentanyl and buprenorphine, and for therapeutic monitoring of the immunosuppressive drugs tacrolimus, sirolimus and cyclosporine. The assays developed are currently being incorporated into routine patient care at the Toxicology Laboratory.

Dr. Cubero Herrera received her PhD in Chemistry from Dalhousie University in 2007. After completing her PhD, she carried out postdoctoral work in Mass Spectrometry at the Saskatchewan Disease Control Laboratory and at the National Research Council Canada in Halifax.

Education

  • PhD: Analytical Chemistry, Dalhousie University
  • MSc: Analytical Chemistry, Dalhousie University
  • BSc: Organic Chemistry, University of Havana

Selected Publications

  • Ramaley, L.; Cubero Herrera, L.; Melanson, J.E. “Quantitative Analysis of TAG in Oils Using Lithium Cationization and Direct-​Infusion ESI Tandem Mass Spectrometry” Journal of the American Oil Chemists' Society, Volume 92, Issue 3, Pages 323-334, 2015.
    Grossert, J.S.; Cubero Herrera, L.; Ramaley, L.; Melanson, J.E. “Studying the Chemistry of Cationized Triacylglycerols Using Electrospray Ionization Mass Spectrometry and Density Functional Theory Computations” Journal of the American Society for Mass Spectrometry,Volume 25, Issue 8, Pages 1421-1440, 2014.
  • Ramaley, L.; Cubero Herrera, L.; Melanson, J.E.”Applicability of non-​linear versus linear fractional abundance calibration plots for the quantitative determination of triacylglycerol regioisomers by tandem mass spectrometry” Rapid Communications in Mass Spectrometry, Volume 27, Issue 11, Pages 1251-1259, 2013.
  • Cubero Herrera, L.; Potvin, M.A.; Melanson, J.E. “Quantitative analysis of positional isomers of triacylglycerols via electrospray ionization tandem mass spectrometry of sodiated adducts” Rapid Communications in Mass Spectrometry, Volume 24, Issue 18, Pages 2745-2752, 2010.
  • Cubero Herrera, L.; Ramaley, L.; Grossert, J.S.”Fragmentation pathways of some benzothiophene radical cations formed by atmospheric pressure chemical ionization” Rapid Communications in Mass Spectrometry, Volume 23, Issue 5, Pages 571-579, 2009.
  • Cubero Herrera, L.; Grossert, J.S.; Ramaley, L.”Quantitative aspects of and ionization mechanisms in positive-​ion atmospheric pressure chemical ionization mass spectrometry” Journal of the American Society for Mass Spectrometry, Volume 19, Issue 12, Pages 1926-1941, 2008.
  • Ramaley, L.; Cubero Herrera, L. “Software for the calculation of isotope patterns in tandem mass spectrometry” Rapid Communications in Mass Spectrometry, Volume 22, Issue 17, Pages 2707-2714, 2008.