Publications
The BMS Core Facility proudly supports researchers in advancing state-of-the-art science through mass spectrometry. Our services are acknowledged in the peer-reviewed research articles listed below, with contributions recognized through authorship or formal acknowledgment.
2025
| Delaidelli et al. (2025). High-resolution proteomic analysis of medulloblastoma clinical samples identifies therapy-resistant subgroups and MYC immunohistochemistry as a powerful outcome predictor. Neuro-Oncology, 27 (9), 2431-2444. DOI: 10.1093/neuonc/noaf046 |
| El-Naggar et al. (2025). Cystathionine gamma-lyase-mediated hypoxia inducible factor 1-alpha expression drives clear cell ovarian cancer progression. Journal of Pathology, 266 (3), 352-367. DOI: 10.1002/path.6433 |
2024
| Takemon et al. (2024). Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities. Genome Medicine, 16 (1) 136. DOI:10.1186/s13073-024-01401-9 |
| Da Costa et al. (2024). Mitochondrial inorganic polyphosphate is required to maintain proteostasis within the organelle. Frontiers in Cell and Developmental Biology, 12:1423208. DOI: 10.3389/fcell.2024.1423208 |
| Neira et al. (2024). Stability of Epinephrine, Norepinephrine, and Phenylephrine for Intravenous Infusions Stored in Three Commercial Plastic Syringe Brands. Anesthesiology, 140 (5) 1047-1049. DOI: 10.1097/ALN.0000000000004944 |
| Madhavi et al. (2024). Defatted Wheat Germ Protein-Derived Peptides Showed Multiple Biological Activities from the Stomach to Small Intestine: In Silico and In Vitro Approaches. Journal of Agricultural and Food Chemistry, 72 (37) 20527-20536. DOI: 10.1021/acs.jafc.4c06539 |
| Nickerson et al. (2024). Impact of Surfactants on Cumulative Trypsin Activity in Bottom-Up Proteome Analysis. Journal of Proteome Research, 23 (8) 3542-3551. DOI: 10.1021/acs.jproteome.4c00162 |
2023
| Cohen et al. (2023). Use of a liquid chromatography-tandem mass spectrometry method to assess the concentration of epinephrine, norepinephrine, and phenylephrine stored in plastic syringes. Pharmaceutical Technology in Hospital Pharmacy, 8 (1): 20220010. DOI: 10.1515/pthp-2022-0010 |
| Rideout et al. (2023). Qualitative Shotgun Proteomics Strategy for Protein Expression Profiling of Fish Otoliths. BioChem, 3 (3), 102-117. DOI:10.3390/biochem3030008 |
| McMillen et al. (2023). A large-scale, targeted metabolomics method for the analysis and quantification of metabolites in human plasma via liquid chromatography-mass spectrometry. Analytica Chimica Acta, 1279:341791. DOI: 10.1016/j.aca.2023.341791 |
| Verburgt et al. (2023). Successful Dietary Therapy in Paediatric Crohn’s Disease is Associated with Shifts in Bacterial Dysbiosis and Inflammatory Metabotype Towards Healthy Controls. Journal of Crohn's and Colitis, 17 (1), 61-72. DOI: 10.1093/ecco-jcc/jjac105 |
| Riveroll et al. (2023). Selection and Validation of Reference Genes for Gene Expression Studies in an Equine Adipose-Derived Mesenchymal Stem Cell Differentiation Model by Proteome Analysis and Reverse-Transcriptase Quantitative Real-Time PCR. Genes, 14 (3):673. DOI:10.3390/genes14030673 |
2022
| Stanton-Turcotte et al. (2022). Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. Journal of Neuroscience, 42 (19) 3931-3948. DOI: 10.1523/JNEUROSCI.0124-22.2022 |
| Nickerson and Doucette (2022). Maximizing Cumulative Trypsin Activity with Calcium at Elevated Temperature for Enhanced Bottom-Up Proteome Analysis. Biology, 11 (10):1444. DOI: 10.3390/biology11101444 |
| Kim et al. (2022). Immune Checkpoint Blockade Augments Changes Within Oncolytic Virus-induced Cancer MHC-I Peptidome, Creating Novel Antitumor CD8 T Cell Reactivities. Molecular and Cellular Proteomics, 21 (2):100182. DOI: 10.1016/j.mcpro.2021.100182 |
| Dahn et al. (2022). Metabolite profiling reveals a connection between aldehyde dehydrogenase 1A3 and GABA metabolism in breast cancer metastasis. Metabolomics, 18 (9). DOI: 10.1007/s11306-021-01864-6 |
| Westhaver et al. (2022). Mitochondrial damage-associated molecular patterns trigger arginase-dependent lymphocyte immunoregulation. Cell Reports, 39 (8):110847. DOI: 10.1016/j.celrep.2022.110847 |
| Rajan et al. (2022). KIT D816V is dimerization-independent and activates downstream pathways frequently perturbed in mastocytosis. British Journal of Haematology, 202 (5) 960-970. DOI: 10.1111/bjh.18116 |
| Ghiboub et al. (2022). Metabolome Changes With Diet-Induced Remission in Pediatric Crohn’s Disease. Gastroenterology, 163 (4) 922-936. DOI: 10.1053/j.gastro.2022.05.050 |
| Sweeney et al. (2022). Analysis of human serum and urine for tentative identification of potentially carcinogenic pesticide-associated N-nitroso compounds using high-resolution mass spectrometry. Environmental Research, 205:112493. DOI: 10.1016/j.envres.2021.112493 |
| Abl-El-Aziz et al. (2022). Heat Shock Alters the Proteomic Profile of Equine Mesenchymal Stem Cells. International Journal of Molecular Sciences, 23 (13):7233. DOI: 10.3390/ijms23137233 |
| Kennedy et al. (2022). NAD+ depletion enhances reovirus-induced oncolysis in multiple myeloma. Molecular Therapy Oncolytics, 24, 695-706. DOI: 10.1016/j.omto.2022.02.017 |
| McCain et al. (2022). Proteomic traits vary across taxa in a coastal Antarctic phytoplankton bloom. The ISME Journal, 16 (2), 569-579. DOI: 10.1038/s41396-021-01084-9 |
| Tavasoli et al. (2022a). Mechanism of action and therapeutic route for a muscular dystrophy caused by a genetic defect in lipid metabolism. Nature Communications, 13 (1):1559. DOI: 10.1038/s41467-022-29270-z |
| Tavasoli et al. (2022b). A mouse model of inherited choline kinase β-deficiency presents with specific cardiac abnormalities and a predisposition to arrhythmia. Journal of Biological Chemistry, 298 (3):101716. DOI: 10.1016/j.jbc.2022.101716 |
2021
| Stum et al. (2021). Genetic analysis of Pycr1 and Pycr2 in mice. Genetics, 218 (1):iyab048. DOI: 10.1093/genetics/iyab048 |
| Behnke et al. (2021). N-linked glycosylation enzymes in the diatom Thalassiosira oceanica exhibit a diel cycle in transcript abundance and favor for NXT-type sites. Scientific Reports, 11 (1):3227. DOI: 10.1038/s41598-021-82545-1 |
| Dunn et al. (2021). Gut bacterial gene changes following pegaspargase treatment in pediatric patients with acute lymphoblastic leukemia. Leukemia & Lymphoma, 62 (13), 3244-3255. DOI: 10.1080/10428194.2021.1953006 |
| McCain et al. (2021). Cellular costs underpin micronutrient limitation in phytoplankton. Science Advances, 7 (32):eabg6501. DOI: 10.1126/sciadv.abg6501 |
| Jakubec and Doucette (2021). Automated Electrokinetic Platform for High-Throughput Sodium Dodecyl Sulfate Depletion Ahead of Proteome Analysis by Mass Spectrometry. Analytical Chemistry, 93 (42), 14042-14047. DOI: 10.1021/acs.analchem.1c03549 |
| St. Paul et al. (2021). Coenzyme A fuels T cell anti-tumor immunity. Cell Metabolism, 33 (12), 2415-2427. DOI: 10.1016/j.cmet.2021.11.010 |
2020
| Diab et al. (2020). NCK1 Regulates Amygdala Activity to Control Context-dependent Stress Responses and Anxiety in Male Mice. Neuroscience, 448:107-125. DOI: 10.1016/j.neuroscience.2020.09.026 |
| Mohandass et al. (2020). TRPM8 as the rapid testosterone signaling receptor: Implications in the regulation of dimorphic sexual and social behaviors. The FASEB Journal, 34 (8), 108887-10906. DOI: 10.1096/fj.202000794r |
| Murphy et al. (2020). Exploring epidermal mucus protease activity as an indicator of stress in Atlantic sturgeon (Acipenser oxyrinchus oxyrhinchus). Journal of Fish Biology, 97 (5), 1354-1362. DOI: 10.1111/jfb.14489 |
| Moser et al. (2020). Protection of the transplant kidney during cold perfusion with doxycycline: proteomic analysis in a rat model. Proteosme Science, 18:3. DOI: 10.1186/s12953-020-00159-3 |
| Nickerson and Doucette (2020). Rapid and Quantitative Protein Precipitation for Proteome Analysis by Mass Spectrometry. Journal of Proteome Research, 19 (5), 2035-2042. DOI: 10.1021/acs.jproteome.9b00867 |
| De Vries et al. (2020). Heat stress response in the closest algal relatives of land plants reveals conserved stress signaling circuits. The Plant Journal, 103 (3), 1025-1048. DOI: 10.1111/tpj.14782 |
| Silva et al. (2020). Demonstration of beta-tropomyosin (Tpm2) and duplication of the alpha-slow tropomyosin gene (TPM3) in Atlantic salmon Salmo salar. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 245:110439. DOI: 10.1016/j.cbpb.2020.110439 |
2019
| McCain and Bertrand (2019). Prediction and Consequences of Cofragmentation in Metaproteomics. Journal of Proteome Research, 18 (10), 3555-3566. DOI: 10.1021/acs.jproteome.9b00144 |
| Wu et al. (2019). Manganese and iron deficiency in Southern Ocean Phaeocystis antarctica populations revealed through taxon-specific protein indicators. Nature Communications, 10 (1):3582. DOI: 10.1038/s41467-019-11426-z |
| Murphy et al. (2019a). Therapy-Induced MHC I Ligands Shape Neo-Antitumor CD8 T Cell Responses during Oncolytic Virus-Based Cancer Immunotherapy. Journal of Proteome Research, 18 (6), 2666-2675. DOI: 10.1021/acs.jproteome.9b00173 |
| Murphy et al. (2019b). Multiplexed Relative Quantitation with Isobaric Tagging Mass Spectrometry Reveals Class I Major Histocompatibility Complex Ligand Dynamics in Response to Doxorubicin. Analytical Chemistry, 91 (8), 5106-5115. DOI: 10.1021/acs.analchem.8b05616 |
| Gaucherand et al. (2019). The Influenza A Virus Endoribonuclease PA-X Usurps Host mRNA Processing Machinery to Limit Host Gene Expression. Cell Reports, 27 (3), 776-792. DOI:10.1016/j.celrep.2019.03.063 |
| Kennedy et al. (2019). Inhibition of Pyruvate Dehydrogenase Kinase Enhances the Antitumor Efficacy of Oncolytic Reovirus. Cancer Research, 79 (15), 3824-3836. DOI: 10.1158/0008-5472.CAN-18-2414 |
| Govaere et al. (2019). Transcriptome and proteome analyses to investigate the molecular underpinnings of cold response in the Colorado potato beetle, Leptinotarsa decemlineata. Cryobiology, 88:54-63. DOI: 10.1016/j.cryobiol.2019.03.011 |
| Daboor et al. (2019). Marine Bacteria, A Source for Alginolytic Enzyme to Disrupt Pseudomonas aeruginosa Biofilms. Marine Drugs, 17 (5):307, DOI: 10.3390/md17050307 |
| Malitan et al. (2019). Knockdown of the small heat-shock protein p26 by RNA interference modifies the diapause proteome of Artemia franciscana. Biochemistry and Cell Biology, 97 (4), 471-479, DOI: 10.1139/bcb-2018-0231 |
2018
| Murphy et al. (2018). The NAD+ Salvage Pathway Supports PHGDH-Driven Serine Biosynthesis. Cell Reports, 24 (9), 2381-2391. DOI: 10.1016/j.celrep.2018.07.086 |
| Runte et al. (2018). Tandem tyrosine phosphosites in the Enteropathogenic Escherichia coli chaperone CesT are required for differential type III effector translocation and virulence. Molecular Biology, 108 (5), 536-550. DOI: 10.1111/mmi.13948 |
| Holloway et al. (2018). Regulation of cell surface protease receptor S100A10 by retinoic acid therapy in acute promyelocytic leukemia (APL)*. Cell Death & Disease, 9 (9):920. DOI: 10.1038/s41419-018-0954-6 |
| Stairs et al. (2018). Microbial eukaryotes have adapted to hypoxia by horizontal acquisitions of a gene involved in rhodoquinone biosynthesis, eLife, 7:e34292. DOI: 10.7554/elife.34292 |
| Pathak et al. (2018). RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers. Molecular Therapy, 26 (8), 2019-2033. DOI: 10.1016/j.ymthe.2018.05.026 |
| Unterlander and Doucette (2018). Membrane-Based SDS Depletion Ahead of Peptide and Protein Analysis by Mass Spectrometry. Proteomics, 18 (9):e1700025. DOI: 10.1002/pmic.201700025 |
2017
| Nersesyan et al. (2017). Oxytocin Modulates Nociception as an Agonist of Pain-Sensing TRPV1. Cell Reports, 21 (6), 1681-1691. DOI: 10.1016/j.celrep.2017.10.063 |
| Clements et al. (2017). Quantitative Temporal in Vivo Proteomics Deciphers the Transition of Virus-Driven Myeloid Cells into M2 Macrophages. Journal of Proteome Research, 16 (9), 3391-3406. DOI: 10.1021/acs.jproteome.7b00425 |
| Aampaw et al. (2017). Observing enzyme ternary transition state analogue complexes by 19F NMR spectroscopy. Chemical Science, 8 (12), 8427-8434. DOI: 10.1039/C7SC04204C |
| Moser et al. (2017). Proteomic Analysis of Perfusate from Machine Cold Perfusion of Transplant Kidneys: Insights Into Protection from Injury. Annals of Transplantation, 22:730-739. DOI: 10.12659/aot.905347 |
| Dembla et al. (2017). Anti-nociceptive action of peripheral mu-opioid receptors by G-beta-gamma protein-mediated inhibition of TRPM3 channels. eLife, 6:e26280. DOI: 10.7554/eLife.26280 |
| Cohen et al. (2017). Analysis of 17β-estradiol, estriol and estrone in American eel (Anguilla rostrata) tissue samples using liquid chromatography coupled to electrospray differential ion mobility tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 31 (10), 842-850. DOI: 10.1002/rcm.7853 |
| Murphy et al. (2017). MHC-I Ligand Discovery Using Targeted Database Searches of Mass Spectrometry Data: Implications for T-Cell Immunotherapies. Journal of Proteome Research, 16 (4), 1804-1816. DOI: 10.1021/acs.jproteome.6b00971 |
| Asuthkar et al. (2017). High-throughput proteome analysis reveals targeted TRPM8 degradation in prostate cancer. Oncotarget, 8:12877-12890. DOI: 10.18632/oncotarget.14178 |
| Güray et al. (2017). Mass Spectrometry of Intact Proteins Reveals +98 u Chemical Artifacts Following Precipitation in Acetone. Journal of Proteome Research, 16 (2), 889-897. DOI: 10.1021/acs.jproteome.6b00841 |
2016
| Dranse et al. (2016). Adipocyte-secreted chemerin is processed to a variety of isoforms and influences MMP3 and chemokine secretion through an NFkB-dependent mechanism. Molecular and Cellular Endocrinology, 436:114-129. DOI: 10.1016/j.mce.2016.07.017 |
| LeBlanc et al. (2016). Competing fragmentation processes of β-substituted propanoate ions upon collision-induced dissociation. Rapid Communications in Mass Spectrometry, 30 (19), 2133-2144. DOI: 10.1002/rcm.7699 |
| Cohen et al. (2016). Determination of Flow Rates in Capillary Liquid Chromatography Coupled to a Nanoelectrospray Source using Droplet Image Analysis Software. Analytical Chemistry, 88 (15), 7476-7480. DOI: 10.1021/acs.analchem.6b01523 |
| Coyle et al. (2016). Breast cancer subtype dictates DNA methylation and ALDH1A3-mediated expression of tumor suppressor RARRES1. Oncotarget, 7 (28), 44096-44112. DOI: 10.18632/oncotarget.9858 |
| Goto et al. (2016). Oxysterol-binding Protein Activation at Endoplasmic Reticulum-Golgi Contact Sites Reorganizes Phosphatidylinositol 4-Phosphate Pools. Journal of Biological Chemistry, 291 (3), 1336-1347. DOI: 10.1074/jbc.M115.682997 |
2015
| Crowell et al. (2015). A two-stage spin cartridge for integrated protein precipitation, digestion and SDS removal in a comparative bottom-up proteomics workflow. Journal of Proteomics, 118:140-150. DOI: 10.1016/j.jprot.2014.09.030 |
| Nagar et al. (2015). Inactivation of Mandelate Racemase by 3-Hydroxypyruvate Reveals a Potential Mechanistic Link between Enzyme Superfamilies. Biochemistry, 54 (17), 2747-2757. DOI: 10.1021/acs.biochem.5b00221 |
| Béliveau et al. (2015). Genomic and Proteomic Analyses Indicate that Banchine and Campoplegine Polydnaviruses Have Similar, if Not Identical, Viral Ancestors. Journal of Virology, 89 (17), 8909-8921. DOI: 10.1128/jvi.01001-15 |
| Elustondo et al. (2015). Activation of the Mitochondrial Permeability Transition Pore Leads to the Increase in Amount of C-Subunit of ATP Synthase Associated with Channel-Forming Complex of Polyhydroxybutyrate and Inorganic Polyphosphate. Biophysical Journal, 108 (2), Supp. 1-608A. DOI: 10.1016/j.bpj.2014.11.3309 |
| Toma et al. (2015). Motoneurons Derived from Induced Pluripotent Stem Cells Develop Mature Phenotypes Typical of Endogenous Spinal Motoneurons. Journal of Neuroscience, 35 (3), 1291-1306. DOI: 10.1523/JNEUROSCI.2126-14.2015 |
| Uchida et al. (2015). Stimulation-dependent gating of TRPM3 channel in planar lipid bilayers. The FASEB Journal, 30 (3), 1306-1316. DOI: 10.1096/fj.15-281576 |
| Davey et al. (2015). The disulfide oxidoreductase SdbA is active in Streptococcus gordonii using a single C-terminal cysteine of the CXXC motif. Molecular Biology, 99 (2), 236-253. DOI: 10.1111/mmi.13227 |
2014
| Adamo et al. (2014). A viral aphrodisiac in the cricket Gryllus texensis. Journal of Experimental Biology, 217 (11), 1970-1976. DOI: 10.1242/jeb.103408 |
| Awad et al. (2014). The unexpected formation of [M − H]+ species during MALDI and dopant-free APPI MS analysis of novel antineoplastic curcumin analogues. Journal of Mass Spectrometry, 49 (11), 1139-1147. DOI: 10.1002/jms.3434 |
2013
| Zheng et al. (2013). A proteomic investigation of apple fruit during ripening and in response to ethylene treatment. Journal of Proteomics, 93: 276-294. DOI: 10.1016/j.jprot.2013.02.006 |
| Cao et al. (2013). Polyester Modification of the Mammalian TRPM8 Channel Protein: Implications for Structure and Function. Cell Reports, 4 (2), 302-315. DOI: 10.1016/j.celrep.2013.06.022 |
| Abdelhady et al. (2013). The progeny of Legionella pneumophila in human macrophages shows unique developmental traits. FEMS Microbiology Letters, 349 (2),99-107. DOI: 10.1111/1574-6968.12300 |
2011
| Kim et al. (2011). Differential chromatin proteomics of the MMS-induced DNA damage response in yeast. Proteome Science, 9:62. DOI: 10.1186/1477-5956-9-62 |
| Steeves et al. (2011). Oxidative stress response in the opportunistic oral pathogen Fusobacterium nucleatum. Proteomics, 11 (10), 2027-2037. DOI: 10.1002/pmic.201000631 |
2010
| Volkmann et al. (2010). Intein-mediated Cyclization of Bacterial Acyl Carrier Protein Stabilizes Its Folded Conformation but Does Not Abolish Function. Journal of Biological Chemistry, 285 (12), 8605-8614. DOI: 10.1074/jbc.M109.060863 |
2009
| Lee et al. (2009). Immune Response and Alveolar Bone Resorption in a Mouse Model of Treponema denticola Infection. Infection and Immunity, 77 (2) , 694- 698. DOI: 10.1128/iai.01004-08 |
| Soundararajan et al. (2009). Triptolide: An inhibitor of a disintegrin and metalloproteinase 10 (ADAM10) in cancer cells. Cancer Biology & Therapy, 8 (21), 2054-2062. DOI: 10.4161/cbt.8.21.9803 |
2007
| Timmons et al. (2007). Exploiting Nucleotidylyltransferases To Prepare Sugar Nucleotides. Organic Letters, 9 (5), 857-860. DOI: 10.1021/ol0630853 |
| Zheng et al. (2007). Qualitative and Quantitative Evaluation of Protein Extraction Protocols for Apple and Strawberry Fruit Suitable for Two-Dimensional Electrophoresis and Mass Spectrometry Analysis. Journal of Agricultural and Food Chemistry, 55 (5), 1663-1673. DOI: 10.1021/jf062850p |
| Potrykus et al. (2007). Proteomic investigation of amino acid catabolism in the indigenous gut anaerobe Fusobacterium varium. Proteomics, 8 (13), 2691-2703. DOI: 10.1002/pmic.200700437 |
| Murphy et al. (2007). Electrospray ionization mass spectra of acyl carrier protein are insensitive to its solution phase conformation. Journal of the American Society for Mass Spectrometry, 18 (8), 1525-1532. DOI: 10.1016/j.jasms.2007.05.012 |