It is home to a research group specializing in lipid and signal transduction. The group is made up of four biochemists and over 25 technicians and trainees. All members are actively involved in university administration, and national and international review panels.
The majority of our research focuses on the synthesis and degradation of membrane lipids like phospholipids and cholesterol. We place emphasis on the relationship between lipid metabolism and human disease, including cancer, neurodegenerative, heart and infectious disease.
Our research also examines the ways these processes contribute to the generation of intracellular "second messengers" involved in cell communication and the ordered trafficking of cellular material in lipid vesicles.
Specific projects include:
the discovery of novel genes and enzymes of lipid metabolism
the regulation of cholesterol and sphingolipid transport
antimicrobial drug design related to bacterial lipid metabolism
apoptosis/anoikis as a tumour-specific therapeutic target
Our other focus is on education. We not only teach advanced science courses related to lipid biochemistry and signal transduction, we also make our ourselves available to help other researchers within the medical school—particularly those working in areas of: