Neuropharmacology & Neurodegenerative Disease
An integrative approach to understanding
Neuropharmacology involves the study of drugs that act on the central nervous system. We employ an integrative approach to understand at the molecular, cellular and neural network levels how such drugs work to influence behaviour.
A major goal of neuropharmacology is to develop treatments that will halt the damaging events responsible for neurodegenerative disorders such as Alzheimer's disease, stroke, retinal degeneration (blindness), Parkinson's disease, multiple sclerosis and Huntington's disease.
Energy failure resulting from impaired mitochondrial function is considered to be a central pathological event in many neurodegenerative disorders. We are working on both small molecule (drug) and gene therapy approaches to protect vulnerable cells of the central nervous system from injury by increasing mitochondrial performance.