Pathobiology of Cancer
Building a better understanding
In the Department of Pathology, cancer biology is a strong research focus. Our researchers work together to develop a deeper understanding of cancer biology, so that we’re better equipped to treat it. We focus on a number of areas including:
- the basic mechanisms of cancer development and progression
- the biological markers for diagnosing cancer and predicting treatment outcomes
- the mechanisms of tumour metastasis
- the mechanisms of chemotherapy resistance and development of novel therapeutics
- the viral oncolytic therapy and cancer immunotherapy
- novel animal models for studying cancer using mice and zebrafish
- the identification and targeting of cancer stem cells
Our researchers
| Dr. Graham Dellaire | Nuclear structure and cancer biology, mechanisms of chemotherapy resistance, zebrafish models of cancer, T-cell leukemia, breast, ovarian, lung and prostate cancer |
| Dr. Paola Marcato | Breast cancer stem cells and chemotherapy resistance |
| Dr. David Waisman | Mechanisms of cancer metastasis, pancreatic and lung cancer |
| Dr. Dan Gaston | Identification of inherited genetic risk factors for cancer |
| Dr. Carman Giacomantonio | Cancer biology, breast, colon and pancreatic cancer |
| Dr. Brent Johnston | Cancer biology, inflammation and immunology, breast and ovarian cancer |
| Dr. Jean Marshall | Cancer biology, inflammation and immunology, mast cells and breast cancer |
| Dr. Shashi Gujar |
Cancer immunotherapies |
| Dr. Alison Wallace | Thoracic surgery |
| Dr. Victor Martinez | Pathology |
| Dr. Amy Trottier | Hematology |