Research and Clinical Trials

Research plays a critical role in advancing cystic fibrosis care. Our clinic is actively involved in research and quality improvement studies that help shape the future of treatment and improve health outcomes for people living with CF. If you're interested in participating in a study or learning more about ongoing efforts, this page offers a summary of research connected to our program and beyond.

Clinical Trials in Nova Scotia

Looking for clinical trials happening near you? Use Cystic Fibrosis Canada’s Trial Finder to explore current and upcoming trials available in Nova Scotia and across Canada.

Visit the Trial Finder

Ongoing Studies and Quality Improvement Projects at Our Clinic

Our team is currently involved in several research initiatives:

• Is semaglutide safe and effective at improving glycemic control in persons with Cystic Fibrosis-Related Diabetes?
• A Longitudinal Study on the Impact of ELX/TEZ/IVA Treatment in Patients with Cystic Fibrosis in the Real World
• Canadian observational study evaluating the long-term IMPACT of CFTR modulators on people with CF (CAN-IMPACT-CF)
• Mapping and Isolation of Genes Influencing Severity of Disease in Cystic Fibrosis
• Improving iron deficiency in cystic fibrosis using a clinic-based protocol (2024)
• Increasing vitamin adherence for people with cystic fibrosis through video-observed therapy (2021)
• Screening for Celiac Disease in Cystic Fibrosis patients (2021)

Additional Research Resources

• Journal Article: The clinical effectiveness of elexacaftor/tezacaftor/ivacaftor (ETI) for people with CF without a F508del variant: A systematic review and meta-analysis
  Read the article

• Canadian Cystic Fibrosis Clinic Data
  Explore the data