Elizabeth Cowley
Professor & Department Head
Related information
PubMed Publications
Email: elizabeth.cowley@dal.ca
Phone: 902-494-3805
Mailing Address:
Room 4F, Sir Charles Tupper Medical Building, 5850 College Street, Halifax, Nova Scotia, Canada B3H 4R2
Research Topics:- Respiratory physiology
- Respiratory disease
- Cystic fibrosis
- Oxidative Stress
Education
- BSc (University College London)
- PhD (University of Leicester)
- PDF (University of California, San Francisco)
- PDF (McGill University)
- PDF (Dalhousie University)
Research interests
Dr. Cowley’s research focuses on the role oxidative stress plays in lung diseases, especially cystic fibrosis. The goal of this research is to understand the fundamental biological mechanisms underlying this stress and use this knowledge to develop novel therapeutic approaches.
Selected publications
- Jones, C.L. Li T. and Cowley E.A. (2012) The Prostaglandin E2 type 4 receptor mediates the response to acute oxidant stress in airway epithelial cells. J Pharmacol Exp Ther 341:552-563.
- Li, T., Qi J., and Cowley E.A. (2011) Activation of the EP4 prostanoid receptor induces prostaglandin E2 and pro-inflammatory cytokine production in human airway epithelial cells. Pulmonary Pharmacology and Therapeutics. 24: 42-48.
- Moser S.L., Harron S., Crack J., Fawcett J. and Cowley E.A. (2008) Multiple KCNQ potassium channel subtypes mediate basal anion secretion from the human airway epithelial cell line, Calu-3 J Membrane Biology 221:153-163.
- Joy A.P and Cowley E.A. (2008) The isoprostane 8-iso-PGE2 stimulates anion secretion across airway epithelial cells via the EP4- prostanoid receptor. Am J Respir Cell Mol Biol 38: 143-152.
- vanTol B., Missan S., Crack J., Moser S., Baldridge W.H., Linsdell P. and Cowley E.A. (2007) Contribution of KCNQ1 to the regulatory volume decrease in the mammary epithelial cell line, MCF-7. Am J Physiol Cell 293:C1010-C1019.
Biography
Dr Cowley received her BSc (Hons) in Pharmacology from University College London in 1989 and her PhD from the University of Leicester in 1993. She did postdoctoral work at the University of California, San Francisco, McGill University and Dalhousie University before joining the faculty of Dalhousie University in 2003.
Teaching
- PHYL 1400: Human Physiology (Respiratory Physiology)
- PHYL 2032: Human Systems Physiology (Respiratory Physiology)
- PHYL 3320: Human Cell Physiology (Cell volume regulation; Epithelial transport)
- PHYL 4504/5504: Respiratory Physiology