Yassine El Hiani
Associate Professor, Director of Graduate Studies
- Ion Channel Structure & Signaling
- Cancer Biology and Signaling
- Cystic fibrosis
- Cell Membrane Signaling
- Organellar Signaling
- Transient Receptor Potential Channels
- CFTR And SLC26A9
- BA/BSc (Ibn Zohr University, Agadir, Morocco)
- MA/MSc (Universite de Picardie Jules Verne, Amiens, Picardie, France)
- PhD (Universite de Picardie Jules Verne, Amiens, Picardie, France)
- PDF (Dalhousie University, Halifax, NS ,Canada)
Dr. El Hiani’s research program critically examines the interface of ion channels and the generation of oxidative stress in the pathophysiology of cancer cells. Using electrophysiological- and molecular-based assays, we study ion channel activity in response to oxidative stress and elucidate the involvement of ion channels in the metabolism, metastasis, survival, and chemoresistance of malignant cells. Our goals are to identify the primary ion channel sensors for oxidative stress, gain molecular insights into the downstream signaling pathways, and understand their functional implications to improve current anticancer therapy. Besides our focus on molecular oncology, we are also interested in exploring the structural changes regulating both the CFTR and SLC26A9 anion channel gating and their functional contribution to Cystic Fibrosis.
Dr. El Hiani is currently reviewing applications from new students. If you are interested in:
- MSc or PhD (Physiology and Biophysics) programs, please email me with the following information: 1) your most recent transcripts (unofficial); 2) your CV and a brief statement describing your research interests and career goals.
- Honours programs (Biology and Medical Sciences) or Directed Project in Medical Sciences, please email me your CV and research interests, at the latest by July 31, 2022, to a define a research project.
- Summer Research Experience, please email me your CV at the latest by December 31, 2022
- Directed Project in Physiology, please email me your CV.
Research Dissemination and Publications:
Students in El Hiani's lab are responsible for completing their projects and disseminating their research findings. Students are expected to present their results at conferences and write draft manuscripts with the help of their supervisor. Many undergraduate and all graduate students in El Hiani's lab have published as co-authors with Dr. El Hiani.
For a complete list of Dr. El Hiani's publications, click here.