Yassine El Hiani

Associate Professor


Email: yassine.elhiani@dal.ca
Phone: 902-494-8980
Fax: 902-494-1684
Mailing Address: 
5G, Tupper Building, 5850 College Street, PO Box 15000, Halifax, Nova Scotia, Canada, B3H 4R2
 
Research Topics:
  • Ion Channel Structure & Signaling
  • Cancer Biology and Signaling
  • Cystic fibrosis
  • Cell Membrane Signaling
  • Organellar Signaling
  • Transient Receptor Potential Channels
  • CFTR And SLC26A9

Education

  • BA/BSc (Ibn Zohr University, Agadir, Morocco)
  • MA/MSc (Universite de Picardie Jules Verne, Amiens, Picardie, France)
  • PhD (Universite de Picardie Jules Verne, Amiens, Picardie, France)
  • PDF (Dalhousie University, Halifax, NS ,Canada)

Research Interests

Dr. El Hiani’s research program critically examines the interface of ion channels and the generation of oxidative stress in the pathophysiology of cancer cells. Using electrophysiological- and molecular-based assays, we study ion channel activity in response to oxidative stress and elucidate the involvement of ion channels in the metabolism, metastasis, survival, and chemoresistance of malignant cells. Our goals are to identify the primary ion channel sensors for oxidative stress, gain molecular insights into the downstream signaling pathways, and understand their functional implications to improve current anticancer therapy. Besides our focus on molecular oncology, we are also interested in exploring the structural changes regulating both the CFTR and SLC26A9 anion channel gating and their functional contribution to Cystic Fibrosis. 

Research Opportunities

Dr. El Hiani is currently reviewing applications from new students. If you are interested in:

Research Dissemination and Publications:

Students in El Hiani's lab are responsible for completing their projects and disseminating their research findings. Students are expected to present their results at conferences and write draft manuscripts with the help of their supervisor. Many undergraduate and all graduate students in El Hiani's lab have published as co-authors with Dr. El Hiani.

For a complete list of Dr. El Hiani's publications, click here.